8 documents found, page 1 of 1
Immunotherapy in lung cancer brain metastases
Paisana, Eunice; Cascao, Rita; Alvoeiro, Magda; Félix, Francisco; Martins, Guilherme; Guerreiro, Carla; Roque, Rafael; Cruz, Rafael Moiteiro DaBrain metastases (BM) occur frequently in lung cancer, particularly in non-small cell lung cancer (NSCLC) patients and remain a significant cause of morbidity and mortality. Standard therapies have limited efficacy due to poor crossing of the blood-brain barrier and the distinct features between BM and the primary tumor. This review explores the immune landscape of brain metastatic disease, emerging immunothera...
Hot Topic In Thoracic Surgery: Can Sublobar Anatomical Resections Be Non-Inferi...
Nawojowska, Agata; Mendes, Samuel; Cabral, Daniel; Gaspar, Marion Emma; Rodrigues, Cristina; Antunes, Mariana; Alvoeiro, Magda; Calado, TelmaBackground: Technological advances and widely spread screening programs enabled the discovery of ever smaller lesions. As such, in the last years, the tendency has shifted towards lung-sparing procedures. The role of limited surgical excision for small peripheral nodules is currently a topic of heated debate. Aim: In our work, we try to answer whether the segmentectomy could adequately treat the peripheral NSCL...
Oncological Outcomes Of Radical Surgery With And Without Induction And Adjuvant...
Nawojowska, Agata; Mendes, Samuel; Gaspar, Marion; Cabral, Daniel; Rodrigues, Cristina; Antunes, Mariana; Alvoeiro, Magda; Calado, TelmaIntroduction: Mesothelioma is a devastating, insidious disease with a long latency period. Its peak incidence occurs in the 5th and 6th decades of life, up to 40 years after asbestos exposure which is strongly related to the disease. The optimal treatment is the object of an intense discussion. Aims: The established outcomes were disease-free survival (DFS) and 1-year survival analyzed in the context of neoadju...
Results Of Minimally Invasive Vats Thymectomy In Miastenia Gravis Patients Comp...
Nawojowska, Agata; Mendes, Samuel; Cabral, Daniel; Rodrigues, Cristina; Antunes, Mariana; Alvoeiro, Magda; Torres, Carolina; Calado, TelmaIntroduction: Myasthenia gravis (MG) is an autoimmune, neurologic disease that causes a wide range of symptoms. While the transsternal, transcervical and thoracotomy approaches are accepted as effective, there is still debate regarding the VATS approach. Materials and Methods: We analyzed our center’s surgical experience with thymectomy for myasthenia gravis, comparing the results of patients operated on using ...
LYMPH NODE UPSTAGING AFTER SURGERY IN PATIENTS WITH NEGATIVE MEDIASTINAL STAGIN...
Cabral, Daniel; Rodrigues, Cristina; Antunes, Mariana; Nawojowska, Agata; Calado, Telma; Torres, Carolina; Alvoeiro, Magda; Mendes, SamuelIntroduction: Mediastinal staging is a hot topic in thoracic oncology. According to the guidelines, and besides other criteria, in the presence of a primary lung cancer with increased mediastinal lymph node uptake on PET-CT, a negative result after lymph node sampling by Endobronchial Ultrasound (EBUS) is not enough to rule out mediastinal lymph node involve- ment, demanding a cervical mediastinoscopy to vouch ...
LUNG RESECTION FOR NON-SMALL-CELL LUNG CANCER - A NEW RISK SCORE TO PREDICT MAJ...
Veiga Oliveira, Paulo; Cabral, Daniel; Antunes, Mariana; Torres, Carolina; Alvoeiro, Magda; Rodrigues, Cristina; Sousa-Uva, Miguel; Félix, FranciscoObjectives: Identify risk factors for major perioperative complications (MPC) after anatomical lung resection for NonSmall-Cell Lung Cancer (NSCLC) and establish a scoring system. Methods: Single center retrospective study of all consecutive patients diagnosed with NSCLC submitted to anatomical lung resection from 2015 to 2019 (N=564). Exclusion criteria: previous lung surgery, concomitant non-lung cancer relat...
SURGICAL TREATMENT OF COMPLICATIONS 55 YEARS AFTER EXTRAPERIOSTEAL LUCITE BALL ...
Calado, Telma; Antunes, Mariana; Alvoeiro, Magda; Félix, FranciscoIn the 1930-50s, before antimicrobial drugs, collapse therapy was the mainstream of treatment for cavitary pulmonary tuberculosis. We present an 78-year-old man with a history of pulmonary tuberculosis treated with plombage in 1962, who presented with axillary pleurocutaneous fistula (Figure 1). The patient was submitted to surgical extraction of 21 lucite balls, pleurocutaneous drainage and thoracoplasty (Figu...
POSTOPERATIVE ATRIAL FIBRILLATION - VIDEO-ASSISTED THORACOSCOPIC SURGERY VERSUS...
Veiga Oliveira, Paulo; Cabral, Daniel; Antunes, Mariana; Torres, Carolina; Alvoeiro, Magda; Rodrigues, Cristina; Sousa-Uva, Miguel; Félix, FranciscoObjectives: Compare the incidence of Postoperative atrial fibrillation (PAF) after anatomical lung resection for Non- Small-Cell Lung Cancer (NSCLC) following open surgery versus VATS. Methods: Single center retrospective study of all consecutive patients diagnosed with NSCLC submitted to anatomical lung resection from 2015 to 2019 (N=564). Exclusion criteria: prior atrial fibrillation, previous lung surgery, c...