Microclimate conditions affect the outdoor urban way of life for humans. These conditions directly impact people’s health and well-being, such as access to medical care or a healthy lifestyle. Human thermal comfort is paramount for people’s health, both physical and mental. In this paper, the study compares two microclimate mobile weather stations (MWS) based on a set of users’-based assessment criteria (usabil...
Saharan dust intrusions over southern Portugal: overall characterization and atmospheric synoptic patterns (2005-2015) Fragoso M, Silva T, Correia E, Vasconcelos J, Lopes A, Carraça MG Saharan dust intrusions are a phenomenon responsible for several environmental impacts over the Mediterranean regions. Regarding the Iberian Peninsula, very scarce studies have addressed this topic in Portugal contrasting to the ...
Background: Sickle cell disease (SCD) is an inherited hematological disorder and a serious global health problem, affecting between 20 and 25 million people worldwide. In Sub-Saharan Africa, where it is more prevalent, it contributes up to 90% of under-5 mortality. Although hydroxyurea (HU) is the leading treatment for these patients, its effects on the gut microbiome have not yet been explored. Some studies re...
Background: In Angola, the prevalence of Sickle Cell Disease (SCD) is almost 2%, and the carriers reach 21% of the population. Although its presentation tends to be very heterogeneous, chronic hemolytic anemia, frequent painful crises, and extensive organ damage are common features of these patients. Pregnancy in SCD patients is associated with an increase in severe outcomes, namely, a high risk of eclampsia an...
Purpose: Sickle cell disease (SCD) is one of the most prevalent genetic disorders, affecting around 20 to 25 million individuals throughout the world. In Sub-Saharan Africa, where it is more prevalent, it can contribute to up to 80% of under-5 mortality. Clinical manifestations of SCD are very heterogeneous and the intestinal microbiome has recently been reported to be crucial in the modulation of inflammation,...
Purpose: Sickle Cell Anaemia (SCA) is an inherited autosomal and lethal blood disorder caused by a mutation in the HBB gene that promotes haemoglobin (Hb) polymerization and consequent sickling of red blood cells (RBCs) in hypoxia. Regardless of being a monogenic disease, SCA has a remarkably high clinical heterogeneity in its phenotypic expression. Several factors have been shown to modulate the clinical manif...
Lemierre's syndrome refers to infectious thrombophlebitis of the internal jugular vein developed as complication of an oropharyngeal infection. It is a rare syndrome, affecting otherwise healthy young adults, which may lead to sepsis complicated by septic embolization. Although there is a characteristic clinical picture, many modern physicians are unaware of this syndrome, leading it to be termed ‘the forgotten...
The study of dust intrusions in Portugal is still a subject on which little investigation has been made, especially in terms of their effects. Thus, this work aims to achieve two goals: firstly, to characterize the dust intrusions in the study area; and secondly, to evaluate the possible statistical association between the dust intrusion days and hospital admissions due to respiratory diseases. Dust intrusions ...
The study of dust intrusions in Portugal is still a subject on which little investigation has been made, especially in terms of their effects. Thus, this work aims to achieve two goals: firstly, to characterize the dust intrusions in the study area; and secondly, to evaluate the possible statistical association between the dust intrusion days and hospital admissions due to respiratory diseases. Dust intrusions ...
The pattern of shell shape variation in populations of the top shell, Phorcus sauciatus from Madeira Island (NE Atlantic) was analysed as a function of substrate type and wave exposure, using geometric morphometrics. We hypothesized that P. sauciatus shows morphological variations to inhabit contrasting environments. Highly significant differences in shell shape were found depending on both substrate type and c...