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Strenuous exercise aggravates MDMA-induced skeletal muscle damage in mice
Duarte, JA; Leao, A; Magalhaes, J; Ascensao, A; Bastos, ML; Amado, FL; Vilarinho, L; Quelhas, D; Appell, HJ; Carvalho, FThe aim of this study was to investigate the influence of ecstasy (MDMA) administration on body temperature and soleus muscle histology in exercised and non-exercised mice. Charles-River mice were distributed into four groups: Control (C), exercise (EX), MDMA treated (M), and M + EX. The treated animals received an i.p. injection (10 mg/kg) of MDMA (saline for C and EX), and the exercise consisted of a 90 min l...
Date: 2005
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Origin: Repositório Aberto da Universidade do Porto