Studying citizens’ lifestyles is extremely important for understanding society and the social conditions of the personal lifestyle. Understanding the lifestyles of university students is especially important because they will be the future citizens and professionals who will shape society’s future. The aim of this study was a systematic review of the scientific literature about the use of the FANTASTIC Lifestyl...
Ovarian cancer is the seventh most common cancer diagnosed in women worldwide. To date, many studies in epithelial ovarian cancer (EOC) have reported on the association HER-2/neu, p53 proteins and steroid hormones and their respective receptors with prognosis and/or the carcinogenesis process, but no definitive conclusion has been reached. Objectives: To assess the proteins c-erbB-2, p53, Ki67 and receptors of ...
Alpha-1-antitrypsin deficiency (AATD) is a genetic autosomal codominant disorder caused by mutations in SERPINA1 gene. It is one of the most prevalent genetic disorders, although it remains underdiagnosed. Whereas at international level there are several areas of consensus on this disorder, in Portugal, inter-hospital heterogeneity in clinical practice and resources available have been adding difficulties in re...
Alpha-1-antitrypsin deficiency (AATD) is a genetic autosomal codominant disorder caused by mutations in SERPINA1 gene. It is one of the most prevalent genetic disorders, although it remains underdiagnosed. Whereas at international level there are several areas of consensus on this disorder, in Portugal, inter-hospital heterogeneity in clinical practice and resources available have been adding difficulties in re...
Life-cycle analyses are used in condition assessment of new and existing bridges as well as for evaluation of maintenance strategies. During the implementation of asset management strategies, maintenance actions are required to keep assets at desired performance levels. In case of roadway bridges, performance indicators, which can be obtained by inspections, non-destructive tests or monitoring systems, are esta...
O presente Manual inscreve-se no quadro de uma pedagogia que considera a iniciação à investigação como um elemento fundamental do processo de ensino/aprendizagem, determinante para a motivação dos alunos e, ao mesmo tempo, garantia da renovação do saber e da descoberta de respostas para os desafios e interrogações do futuro. Podemos apontar como intenção primeira, suscitar no leitor uma compreensão efectiva da ...
Synthesis of 10-membered bislactones by PCC oxidation of methyl 2,6-di-O-pivaloyl-α-D-glucopyranoside and methyl 4,6-O-benzylidene-α-D-glucopyranoside is described, with emphasis on their structure elucidation using the information gained by combination of NMR spectroscopic techniques with X-ray diffraction data. In alternative, the use of PCC and PCC adsorbed on silica gel or alumina for the regioselective oxi...