5 documents found, page 1 of 1
Relationship between fluid-attenuated inversion-recovery (FLAIR) signal intensi...
Varella,Pedro Paulo Vasconcellos; Santiago,Joselita Ferreira Carvalho; Carrete Jr.,Henrique; Higa,Elisa Mieko Suemitsu; Yacubian,Elza Márcia TargasWe investigated a relationship between the FLAIR signal found in mesial temporal sclerosis (MTS) and inflammation. Twenty nine patients were selected through clinical and MRI analysis and submitted to cortico-amygdalo-hippocampectomy to seizure control. Glutamate, TNFα, IL1, nitric oxide (NO) levels and immunostaining against IL1β and CD45 was performed. Control tissues (n=10) were obtained after autopsy of pat...
Neurogenesis induced by seizures in the dentate gyrus is not related to mossy f...
Sanabria,Yaima del Carmen Garrido; Argañaraz,Gustavo Adolfo; Lima,Eliangela; Priel,Margareth Rose; Trindade,Edvaldo da Silva; Loeb,Luana MazzacorattiNeurogenesis in the dentate gyrus (DG) has attracted attention since abnormal supragranular mossy fiber sprouting occurs in the same region, in temporal lobe epilepsy. Thus, we submitted developing rats to pilocarpine-induced status epilepticus (SE) to study the relationship between neurogenesis and mossy fiber sprouting. Groups were submitted to SE at: I-P9, II-P7, P8 and P9, III-P17 e IV-P21. Neurogenesis was...
Estudo comparativo entre enxerto autógeno e enxerto muscular coberto com tubo d...
Fernandes,Marcela; Valente,Sandra Gomes; Amado,Débora; Fernandes,Maria José da Silva; Naffah-Mazzacoratti,Maria da Graça; Santos,João Baptista Gomes dosEste trabalho teve como objetivo o estudo da regeneração nervosa através da contagem de neurônios comparando duas técnicas cirúrgicas no tratamento da perda de substância nervosa nos membros inferiores em 15 ratos. Inicialmente obteve-se tubo de veia de 12mm de comprimento retirado da jugular externa esquerda. A seguir, opera-se os dois membros inferiores, expondo o nervo tibial de cada lado e ressecando um seg...
Efeito neuroprotetor da melatonina e N-acetilserotonina na epileptogênese e no ...
Lima,Eliângela de; Cabral,Francisco Romero; Cavalheiro,Esper Abrão; Naffah-Mazzacoratti,Maria da Graça; Amado,DéboraPURPOSE: The aim of this research was to study the effects of treatment with melatonin and N-acetilserotonin in the development of pilocarpina model of epilepsy in adult male rats. METHODS: Part I - The animals were divided in 4 groups: SALINE - animals that received only saline; SE - animals submitted to status epilepticus (SE); NAS + SE - animals that received pre-treatment with N-acetylserotonin and were sub...
Effect of glycemic state in rats submitted to status epilepticus during develop...
Santiago,Joselita F.C.; Carvalho,Fatima F.; Perosa,Sandra R.; Siliano,Marcelo R.; Cruz,José Walber M.C.; Fernandes,Maria José S.; Cavalheiro,Esper A.The effect of glycemic state on status epilepticus (SE) development was studied in animals of different ages, submitted to pilocarpine model of epilepsy. Groups: I- Rats with 9-day-old (P9): IA. Submitted to 1SE; IB. Saline-treated; IC. Induced- hyperglycemia; ID. Induced- hyperglycemia+SE; II- Rats submitted to three consecutive episodes of SE at P7, P8 and P9; III- Rats submitted to 1SE at P17; IV- Rats submi...