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Long-term sex differences in symptoms and immune profile in long COVID

Feliz, José; Gonçalves, Juliana; Cabedo, Carolina; Brito, José; Gamas, Maria; Neves, Maria Inês; Soares, Helena

Background: Long COVID (LC) is a post-infectious condition affecting millions worldwide, characterized by persistent multisystem symptoms. Females are disproportionately affected, reporting higher symptom burden, particularly neurocognitive and neurosensory complaints. While short-term immunopathology has been described, the long-term clinical course, immune dysregulation, and sex-specific underpinnings remain ...


Immunophenotyping of palatine tonsils in children with OSAS versus recurrent to...

Chantre, Tiago; Gonçalves, Juliana; Cerqueira, Sofia A.; Nascimento, João; Soares, Helena; Moreira, Inês Alpoim; Barroso, Mafalda; Sousa, Herédio

Introduction - Obstructive Sleep Apnea Syndrome (OSAS) and Recurrent Tonsillitis (RA) are the main indications for performing tonsillectomy in children. Despite the growing knowledge in tissue immunology of palatine tonsils, the pathophysiology that leads to the development of OSAS or RA is not fully known. Objectives - Comparative immunophenotypic analysis of children with OSAS versus RA. The epidemiological s...


Balance between maternal antiviral response and placental transfer of protectio...

Gonçalves, Juliana; Melro, Magda; Alenquer, Marta; Araújo, Catarina; Castro-Neves, Júlia; Amaral-Silva, Daniela; Ferreira, Filipe; Ramalho, José S.

The intricate interplay between maternal immune response to SARS-CoV-2 and the transfer of protective factors to the fetus remains unclear. By analyzing mother-neonate dyads from second and third trimester SARS-CoV-2 infections, our study shows that neutralizing antibodies (NAbs) are infrequently detected in cord blood. We uncovered that this is due to impaired IgG-NAb placental transfer in symptomatic infectio...


Efeito de diferentes tipos de cirurgia bariátrica no perfeil lipídico de doente...

Santos, Sara Gil; Calheiros, Raquel; Silva, Maria Manuel; Canha, Marta Borges; Moreno, Telma; Ribeiro, Sara; Gonçalves, Juliana; Ferreira, Helena Urbano


Sex-based differences in T cell response

Gonçalves, Juliana

RESUMO: A investigação é essencial para compreender o sistema imunitário e destrinçar os mecanismos de doença. No entanto, a maioria dos estudos realizados não consideram as diferenças sexuais como variável. No caso especifico das mulheres, estas desenvolvem uma resposta imunitária mais forte, o que contribui não só para a rápida eliminação de agentes patogénicos, mas também para um aumento da eficácia na vacin...


Staff SARS-CoV-2 Seroprevalence and Mental Health as Key Factors in University ...

Lopes, David; Oliveira Henriques, Ana Rita; Santos-Dias, Margarida; Nunes-Da-Silva, Catarina; Gonçalves, Juliana; Sousa, RD; Abdulghani, Saba

Copyright © 2021 Lopes, Henriques, Santos-Dias, Nunes-da-Silva, Gonçalves, de Sousa, Abdulghani, Eletério, Braga, Soares, Branco, Canhão and Rodrigues.; Background: In response to rapid global spread of the newly emerged coronavirus disease 2019 (COVID-19), universities transitioned to online learning and telework to decrease risks of inter-person contact. To help administrators respond to the COVID-19 pandemic...


Internationalization in the hotel industry and modes of entry

Moskalenko, Anna Sergiyvna; da Silva, Inês Cruz Reis da; Gonçalves, Juliana; Brito, Mafalda; Moreira, Antonio


Evaluating SARS-CoV-2 Seroconversion Following Relieve of Confinement Measures

Gonçalves, Juliana; Sousa, Rita L.; Jacinto, Maria J.; Silva, Daniela A.; Paula, Filipe; Sousa, RD; Zahedi, Sara; Carvalho, Joana; Cabral, MG

Funding: This work was supported by FCT grants (PTDC/MECREU/29520/2017 to HS and CHRC UIDB/4923/2020, UIPD/4923/2020). JG, MJJ, and DAS are supported by FCT through /BD/128343/2017, PTDC/EGE-OGE/32573/2017, and PD/BD/137409/2018, respectively. The anti-SARSCoV-2 ELISA assay was developed within the context of Serology4COVID consortium, in which IBET (Instituto de Biologia Experimental e Tecnológica) produced an...


Evaluating SARS-CoV-2 seroconversion following relieve of confinement measures

Gonçalves, Juliana; Sousa, Rita L.; Jacinto, Maria J.; Silva, Daniela A.; Paula, Filipe; Sousa, Rute; Zahedi, Sara; Carvalho, Joana

Seroprevalence studies are crucial both for estimating the prevalence of SARS-CoV-2 exposure and to provide a measure for the efficiency of the confinement measures. Portuguese universities were closed on March 16th 2020, when Portugal only registered 62 SARS-CoV-2 infection cases per million. We have validated a SARS-CoV-2 ELISA assay to a stabilized full-length spike protein using 216 pre-pandemic and 19 mole...


Práticas de gerenciamento de projetos públicos a partir das Transferências Volu...

Gonçalves, Juliana

Submitted by Alison Souza (alisonsouza@ufgd.edu.br) on 2019-06-05T19:40:12Z No. of bitstreams: 1 JulianaGoncalves.pdf: 2943924 bytes, checksum: c7e57ac75c00ffc554361545a7009b8d (MD5); Made available in DSpace on 2019-06-05T19:40:12Z (GMT). No. of bitstreams: 1 JulianaGoncalves.pdf: 2943924 bytes, checksum: c7e57ac75c00ffc554361545a7009b8d (MD5) Previous issue date: 2018-09-14; O município é responsável em soluc...

Data: 2019   |   Origem: Oasisbr

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