26 documents found, page 1 of 3
Building a Portuguese coalition for biodiversity genomics
Marques, João; Alves, Paulo; Amorim, Isabel; Lopes, Ricardo; Moura, Mónica; Meyers, Eugene; Sim-sim, Manuela; Sousa-Santos, Carla; Alves, JuditeThe diverse physiography of the Portuguese land and marine territory, spanning from continental Europe to the Atlantic archipelagos, has made it an important repository of biodiversity throughout the Pleistocene glacial cycles, leading to a remarkable diversity of species and ecosystems. This rich biodiversity is under threat from anthropogenic drivers, such as climate change, invasive species, land use changes...
Adipose gene expression profiles in Northern Finncattle, Mirandesa cattle, Yaku...
Ruvinskiy, Daniil; Amaral, Andreia; Weldenegodguad, Melak; Ammosov, Innokentyi; Honkatukia, Mervi; Heli, Lindeberg; Peippo, Jaana; Popov, RuslanThe drastic change in global climate has led to in-depth studies of the geneticresources of native cattle adapted to challenging environments. Native cattle breeds may harbor unique genetic mechanisms that have enabled them adapt to their given environmental conditions. Adipose tissues are key factors in the regulation of metabolism and energy balance and are crucial for the molecular switches needed to adapt t...
Evaluation of multidrug-resistant bacteria and their molecular mechanisms found...
Silva, Joana; Menezes, Juliana; Fernandes, Laura; Marques, Cátia; Costa, Sofia; Dorina, Timofte; Amaral, Andreia; Pomba, ConstançaIntroduction: Intensive medical care provided in companion animal practices carries the potential risk of selecting and disseminating multidrug-resistant organisms (MDROs). However, data on infection, prevention and control standards specific to small animal veterinary practices (SAVPs) remains limited. The goal of our work was to evaluate the environmental contamination and staff carriage by MDROs in veterinar...
Empowering bioinformatics communities with Nextflow and nf-core
Langer, Björn; Amaral, Andreia; ..., ...; Notredame, CedricStandardized analysis pipelines contribute to making data bioinformatics research compliant with the paradigm of Findability, Accessibility, Interoperability, and Reusability (FAIR), and facilitate collaboration. Nextflow and Snakemake, two popular command-line solutions, are increasingly adopted by users, complementing GUI-based platforms such as Galaxy. We report recent developments of the nf-core framework w...
Claudin and Rab proteins are key molecular components involved in coccidiosis r...
Varela-Martínez, Endika; Afonso, Ana; Mainou, Dimitra; Teixeira, Fábio; Nunes, Telmo; Vieira, Pedro; Sarraguça, Inês; Martins, CristinaBackground Although coccidial infection is often asymptomatic in sheep, both clinical and subclinical forms of the disease are linked to considerable production losses, mainly in young lambs. Studies aiming to identify genetic markers for use in selection programs towards increasing genetic resistance to coccidiosis are lacking and have yet to be performed in Portuguese Merino sheep. The purpose of this study w...
Genomic characterisation of endangered Landim pigs reveals distinctive features...
Teixeira, Fábio; Sá, Pedro; Santos, Dulce; Garrine, Carmen; Zimba, Rosa; Augusto, Laurinda; Varela-Martinez, Varela; Chiaia, HermenegildoIntroduction: The Landim pigs of Mozambique are an important local breed, reared by smallscale farmers in extensive systems, predominantly sustained on leftover food. These pigs serve as a cornerstone of the economic stability of these communities. However, their existence is currently threatened by uncontrolled crossbreeding with commercial pig breeds. Preserving these local pigs is also crucial, given their r...
Projeto SUMO: Sustentabilidade do Montado - Uma abordagem multidisciplinar ao e...
Charneca, Rui; Bettencourt, Elisa; Padre, Ludovina; Nunes, Telmo; Martins, José Manuel; Serrano, João; Pereira, Alfredo; Sales-Baptista, ElviraO projeto “SUMO: Sustentabilidade do Montado” pretende contribuir para o conhecimento e valorização do ecossistema Montado e tem como foco principal a produção animal e a sua compatibilização com a manutenção e promoção da biodiversidade vegetal, animal e micológica, no sentido de promover uma produção agropecuária sustentável e resiliente. O projeto SUMO envolve 15 parceiros entre os quais duas Instituições de...
Key co-expressed genes correlated with blood serum parameters of pigs fed with ...
Fanalli, Simara; Gomes, Julia; Novais, Francisco; Gervásio, Izally; Fukumazu, Heidge; Moreira, Gabriel; Coutinho, Luiz; Koltes, James; Amaral, AndreiaThis study investigated how gene expression is affected by dietary fatty acids (FA) by using pigs as a reliable model for studying human diseases that involve lipid metabolism. This includes changes in FA composition in the liver, blood serum parameters and overall metabolic pathways. RNA-Seq data from 32 pigs were analyzed using Weighted Gene Co-expression Network Analysis (WGCNA). Our aim was to identify chan...
Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharingbetwe...
Menezes, Juliana; Frosini, Siân-Marie; Belas, Adriana; Marques, Cátia; Silva, Joana; Amaral, Andreia; Loeffler, Anette; Pomba, ConstançaExtended-spectrum beta-lactamase (ESBL)- and plasmid-mediated cephalosporinase (AmpC)-producing Enterobacterales (ESBL/AmpC-E) are an increasing healthcare problem in both human and veterinary medicine. The aim of this study was to investigate the possible sharing of ESBL/AmpC-E strains between healthy companion animals and humans of the same household in Portugal (PT) and the United Kingdom (UK). In a prospect...
Dynamics of blaOXA-23 gene transmission in Acinetobacter spp. from contaminated...
Silva, Joana; Menezes, Juliana; Fernandes, Laura; Marques, Cláudia; Costa, Sofia; Timofte, D.; Amaral, Andreia; Pomba, C.Background Carbapenem-resistant Acinetobacter baumannii is a common pathogen associated with healthcare-acquired infections, and robust infection prevention and control protocols exist in human healthcare settings. In contrast, infection prevention and control (IPC) standards are limited in veterinary medicine, necessitating further investigation. Aim Examine the possible transmission of carbapenem-resistant Ac...