82 documents found, page 1 of 9
Chitosan nanoparticles for enhanced immune response and delivery of multi-epito...
Amaral, Rita; Concha, Tomás; Vítor, Jorge; Almeida, António J.; Calado, Cecília; Diogo Gonçalves, Lídia MariaHelicobacter pylori is the leading cause of chronic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosal-associated lymphoma. Due to the emerging problems with antibiotic treatment against H. pylori in clinical practice, H. pylori vaccination has gained more interest. Oral immunization is considered a promising approach for preventing initial colonization of this bacterium in the gastrointestinal tract,...
Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spe...
Rocha, Gustavo; Soares, Paulo; Flor-de-Lima, Filipa; Amaral, RitaIntroduction: The challenge of maintaining normoxemia in preterm infants undergoing respiratory support and oxygen therapy has led to the development of closed-loop automatic control systems for FiO2. The aim of this study was to assess the effectiveness of these systems in maintaining SpO2 within a target range (90% - 94%) in preterm neonates receiving supplemental oxygen.Methods: We conducted a single-centre ...
Adherence to treatment in allergic rhinitis during the pollen season in Europe:...
Bousquet, Jean; Amaral, RitaAdherence to rhinitis treatment has been insufficiently assessed. We aimed to use data from the MASK-airmHealth app to assess adherence to oral antihistamines (OAH), intra-nasal corticosteroids (INCS) or azelastine-fluticasone inpatients with allergic rhinitis. We included regular European MASK-air users with self-reported allergic rhinitis and reporting at least 1 day of OAH,INCS or azelastine-fluticasone. We ...
Comparison of allergic rhinitis treatments on patient satisfaction: A MASK-air ...
Bousquet, Jean; Amaral, RitaSatisfaction with treatments may affect medication adherence and use patterns, including the use of comedication. We aimed to compare different medications for allergic rhinitis (AR) on (i) patients' satisfaction and (ii) co-medication use frequency. We assessed data from the mHealth app MASK-air. We evaluated days on which users with self-reported AR had used—alone or in co-medication—intranasal corticosteroid...
Control of allergic rhinitis and asthma test for children (CARATkids): A system...
Didi, Hadla Sami El; Pereira, Ana Margarida; Jácome, Cristina; Amaral, Rita; Wandalsen, Gustavo F.; Emons, Joyce; Grutta, Stefania LaControl of Allergic Rhinitis and Asthma Test for Children (CARATkids) is the first patient-reported outcome measure (PROM) designed to assess both allergic rhinitis and asthma simultaneously in children aged 6 to 12 years. CARATkids has been validated in several languages and countries, highlighting the need for a review of its psychometric properties. This study aims to evaluate the measurement properties of C...
Allergic rhinitis and work productivity: Preliminary analysis of data from the ...
Ferreira, Laura; Pinto, Bernardo Sousa; Alves, Sandra Maria; Amaral, Rita; Alves, Sandra Maria; Amaral, RitaAllergic rhinitis is a health condition more prevalent in developed countries that can impact the activities and quality of life of affected individuals1. Although its impact on work productivity is recognized2, there is still a need for a more detailed understanding and quantification. This cross-sectional observational study investigates the relationship between allergic rhinitis and work productivity, using ...
Understanding beliefs about inhaled medication in patients with persistent asth...
Novais, Catarina; Cruz, Ana Margarida; Pereira, Ana Margarida; Almeida, Rute; Amaral, Rita; Fonseca, João Almeida; Jácome, CristinaIdentifying factors influencing adherence, such as patients’ beliefs about medication, is essential for effective asthma management. This study aims to assess and gain insight into the beliefs of patients with asthma regarding inhaled medication. This is a secondary analysis of the INSPIRERS studies. Patients aged ≥ 13 y.o., with persistent asthma and a prescription for inhaled controller were recruited from 60...
Patients' health care resources utilization and costs estimation across cardiov...
Gavina, Cristina; Borges, Alexandra; Afonso-Silva, Marta; Fortuna, Inês; Canelas-Pais, Mariana; Amaral, Rita; Costa, Inês; Seabra, Daniel"Atherosclerotic Cardiovascular Disease (ASCVD) is a global public health concern. This study aimed to estimate the healthcare resource utilization (HRU) and costs stratified by cardiovascular disease (CVD) risk categories using real-world evidence, in a regional population in Portugal. This is a retrospective observational study, using data from Electronic Health Records between 2017 and 2021. Patients aged≥40...
Concepts for the Development of Person-Centered, Digitally Enabled, Artificial ...
Bousquet, Jean; Amaral, Rita; Amaral, RitaThe traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients’ resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people...
Concepts for the Development of Person-Centered, Digitally Enabled, Artificial ...
Bousquet, Jean; Schünemann, Holger; Sousa-Pinto, Bernardo; Zuberbier, Torsten; Togias, Alkis; Samoliński, Bolesław; Bedbrook, AnnaAbstract The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure th...