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An injectable composite co‐assembled dehydropeptide‐based magnetic/plasmonic li...

Veloso, Sérgio R. S.; Vázquez‐González, Margarita; Spuch, Carlos; Freiría‐Martínez, Luis; Comís‐Tuche, María; Iglesias‐Martínez‐Almeida, Marta

Advancing therapeutic effectiveness through the strategic co-delivery of drugs in a sequential manner represents a compelling strategy. However, achieving precise and selective release of chemotherapeutic agents remains a formidable challenge. In this study, a co-assembled Arginine-Glycine-Aspartate (RGD)-functionalized dehydropeptide-based gel loaded with magnetic liposomes and mesoporous silica-coated gold na...


Extracting phonon coupling parameters from multi color center photoluminescence

Lamelas, A.; Amaral, V. S.

Vibronic coupling of color centers plays a crucial role in their effectiveness for quantum technologies. This study presents a novel approach to extract key parameters, including the Huang-Rhys factor and the one-phonon coupling function, from photoluminescence spectra containing the signal from multiple color centers. Monotonic splines are used to represent the one-phonon coupling function, optimized using a v...


Tuning the drug multimodal release through a co-assembly strategy based on magn...

Veloso, Sergio R. S.; Tiryaki, Ecem; Spuch, Carlos; Hilliou, L.; Amorim, C. O.; Amaral, V. S.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.

Self-assembled short peptide-based gels are highly promising drug delivery systems. However, implementing a stimulus often requires screening different structures to obtain gels with suitable properties, and drugs might not be well encapsulated and/or cause undesirable effects on the gel's properties. To overcome this challenge, a new design approach is presented to modulate the release of doxorubicin as a mode...


Nanoscopic photoluminescence memory as a fingerprint of complexity in self-asse...

Carlos, L. D.; Amaral, V. S.; Silva, N. J.; Sá Ferreira, R. A.; Rocha, J.; De Zea Bermudez, V.; Nunes, S. C.; Santilli, C. [UNESP]

Made available in DSpace on 2022-04-28T18:56:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-12-01; Phys. Dep. CICECO Aveiro University; Chem. Dep. CICECO Aveiro University; Chem. Dep. CQ-VR UTAD University; Chemistry Institute Unesp, Araraquara, S.P.; Chemistry Institute Unesp, Araraquara, S.P.

Date: 2022   |   Origin: Oasisbr

Tuning the drug multimodal release through a co-assembly strategy based on magn...

Veloso, Sérgio R. S.; Tiryaki, Ecem; Spuch, Carlos; Hilliou, Loic; Amorim, C. O.; Amaral, V. S.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.

Self-assembled short peptide-based gels are highly promising drug delivery systems. However, implementing a stimulus often requires screening different structures to obtain gels with suitable properties, and drugs might not be well encapsulated and/or cause undesirable effects on the gel's properties. To overcome this challenge, a new design approach is presented to modulate the release of doxorubicin as a mode...


Novel magnetoliposomes based on shape-anisotropic nanoparticles for combined ch...

Cardoso, Beatriz D.; Rodrigues, Ana Rita Oliveira; Bañobre-Lopez. M.; Almeida, B. G.; Amorim, Carlos O.; Amaral, V. S.; Coutinho, Paulo J. G.

In this work, a new method for magnetoliposomes synthesis with improved and adequate structural, physicochemical and magnetic properties was developed. The overall results confirmed the development of a promising new method for the synthesis of cubic-shaped magnetic ferrite nanoparticles and a novel route for drug-loaded SMLs with improved features. The properties of these multifunctional nanosystems point to t...


Deposition of Lu-Fe-O thin films on silica glass substrates by MOCVD

Cardoso, A. F.; Bassou, A. A.; Amaral, V. S.; Fernandes, J. R.; Tavares, Pedro

Thin films of the Lu-Fe-O system were deposited by aerosol assisted MOCVD on silica glass substrates. Hexagonal h-LuFeO3, garnet Lu3Fe5O12, perovskite o-LuFeO3 or hematite Fe2O3 phases were obtained, depending on the thermodynamic deposition conditions or post annealing temperature. Magnetic measurements confirm the ferromagnetic behaviour at room temperature of the thin films with garnet phase. An indirect ban...

Date: 2020   |   Origin: Repositório da UTAD

Stealth magnetoliposomes based on calcium-substituted magnesium ferrite nanopar...

Cardoso, Beatriz D.; Rodrigues, Ana Rita Oliveira; Almeida, B. G.; Amorim, C. O.; Amaral, V. S.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.

In this work, stealth (aqueous and solid) magnetoliposomes containing calcium-substituted magnesium ferrite nanoparticles, CaxMg1-xFe2O4 (with x = 0.25, 0.50, 0.75) were developed as nanocarriers for curcumin, following previously developed work [3]. Magnetic nanoparticles were synthesized by coprecipitation method and characterized on their colloidal stability and optical, magnetic and structural properties.


Dehydropeptide-based plasmonic magnetogels: a supramolecular composite nanosyst...

Veloso, Sérgio Rafael Silva; Martins, J. A. R.; Hilliou, L.; Amorim, C. O.; Amaral, V. S.; Almeida, B. G.; Jervis, Peter John; Moreira, R.

Supramolecular hydrogels are highly promising for biomedical materials owing to the wide array of properties that can be tailored and modulated. The combination with plasmonic/magnetic nanoparticles into plasmonic magnetogels further improve its potential in biomedical applications, through the combination of complementary strategies, such as photothermia, magnetic hyperthermia, photodynamic therapy and magneti...


Constrained titanohematite formation at BTO/Fe interfaces deposited by RF-sputt...

Amorim, C.O.; Sloyan, K.; Correia, M. R.; Lourenço, A. A.C.S.; Dahlem, M.S.; Amaral, V. S.

The usage of heterostructures of ferromagnetic and ferroelectric materials, as a means of achieving magnetoelectric multiferroic coupling, is a widely used approach which has been showing promising results. Along this line of thought, the deposition of BaTiO3 and Fe multilayers on LaAlO3, MgO, Al2O3 and SrTiO3 substrates using RF-magnetron sputtering was carried out to study its viability to produce magnetoelec...


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