6 documents found, page 1 of 1
The role of nanohydroxyapatite on the morphological, physical, and biological p...
Sato, Tabata P. [UNESP]; Rodrigues, Bruno V. M.; Mello, Daphne C. R. [UNESP]; Münchow, Eliseu A.; Ribeiro, Juliana S.; Machado, João Paulo B.Made available in DSpace on 2021-06-25T10:13:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Objectives: This study aimed to evaluate the effects of nanohydroxyapatite (nHAp) particles on the morphological, chemical, physical, and biological properties of chitosan...
NIK1-mediated translation suppression functions as a plant antiviral immunity m...
Zorzatto, Cristiane; Machado, João Paulo B.; Lopes, Kênia V. G.; Nascimento, Kelly J. T.; Pereira, Welison A.; Brustolini, Otávio J. B.Plants and plant pathogens are subject to continuous co-evolutionary pressure for dominance, and the outcomes of these interactions can substantially impact agriculture and food security^ 1–3 . In virus– plant interactions, one of the major mechanisms for plant antiviral immunity relies on RNA silencing, which is often suppressed by co-evolving virus suppressors, thus enhancing viral pathogenicity in susceptibl...
Translational control in plant antiviral immunity
Machado, João Paulo B.; Iara P., Calil; Santos, Anésia A.; Fontes, Elizabeth P.B.Due to the limited coding capacity of viral genomes, plant viruses depend extensively on the host cell machinery to support the viral life cycle and, thereby, interact with a large number of host proteins during infection. Within this context, as plant viruses do not harbor translation-required components, they have developed several strategies to subvert the host protein synthesis machinery to produce rapidly ...
The ribosomal protein L10/QM-like protein is a component of the NIK-mediated an...
Rocha, Carolina S.; Santos, Anésia A.; Machado, João Paulo B.; Fontes, Elizabeth P.B.The NIK (NSP-interacting kinase)-mediated antiviral signaling pathway was identified as a virulence target of the begomovirus nuclear shuttle protein (NSP). Here, we further characterized this layer of plant innate defense by identifying the ribosomal protein L10 (rpL10), a QM-like protein, as a downstream effector of the antiviral signaling. Although both ribosomal proteins rpL10 and rpL18 were found to associ...
Immune receptors and co-receptors in antiviral innate immunity in plants
Gouveia, Bianca C.; Calil, Iara P.; Machado, João Paulo B.; Santos, Anésia A.; Fontes, Elizabeth P. B.Plants respond to pathogens using an innate immune system that is broadly divided into PTI (pathogen-associated molecular pattern- or PAMP-triggered immunity) and ETI (effector-triggered immunity). PTI is activated upon perception of PAMPs, conserved motifs derived from pathogens, by surface membrane-anchored pattern recognition receptors (PRRs). To overcome this first line of defense, pathogens release into pl...
Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a defense s...
Carvalho, Claudine M.; Santos, Anésia A.; Pires, Silvana R.; Rocha, Carolina S.; Saraiva, Daniela I.; Machado, João Paulo B.; Mattos, Eliciane C.The NSP-interacting kinase (NIK) receptor-mediated defense pathway has been identified recently as a virulence target of the geminivirus nuclear shuttle protein (NSP). However, the NIK1–NSP interaction does not fit into the elicitor–receptor model of resistance, and hence the molecular mechanism that links this antiviral response to receptor activation remains obscure. Here, we identified a ribosomal protein, r...