6 documents found, page 1 of 1
Frequency of MELAS Main Mutation in a Phenotype-Targeted Young Ischemic Stroke ...
Tatlisumak, T; Putaala, J; Innilä, M; Enzinger, C; Metso, TM; Curtze, S; von Sarnowski, B; Amaral-Silva, A; Jungehulsing, GJ; Tanislav, C; Thijs, VMitochondrial diseases, predominantly mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), may occasionally underlie or coincide with ischemic stroke (IS) in young and middle-aged individuals. We searched for undiagnosed patients with MELAS in a target subpopulation of unselected young IS patients enrolled in the Stroke in Young Fabry Patients study (sifap1). Among the 3291 IS pat...
Frequency of MELAS main mutation in a phenotype-targeted young ischemic stroke ...
Tatlisumak, T; Putaala, J; Innilä, M; Enzinger, C; Metso, TM; Curtze, S; von Sarnowski, B; Amaral-Silva, A; Jungehulsing, GJ; Tanislav, C; Thijs, VMitochondrial diseases, predominantly mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), may occasionally underlie or coincide with ischemic stroke (IS) in young and middle-aged individuals. We searched for undiagnosed patients with MELAS in a target subpopulation of unselected young IS patients enrolled in the Stroke in Young Fabry Patients study (sifap1). Among the 3291 IS pat...
Thrombolysis in Patients Aged over 80 Years Is Equally Effective and Safe
Pego, PM; Nunes, AP; Ferreira, P; Sousa, C; Amaral-Silva, ABACKGROUND: Despite stroke's high prevalence in the elderly, intravenous thrombolysis is licensed in Europe only for patients younger than 80 years old. We aimed to compare the functional outcomes and complication rates in patients older versus younger than 80 years old treated with intravenous thrombolysis. METHODS: A retrospective observational study of patients who received intravenous thrombolysis in a stro...
Thrombolysis in Patients Aged over 80 Years Is Equally Effective and Safe
Pego, PM; Paiva Nunes, A; Ferreira, P; Sousa, C; Amaral-Silva, ABACKGROUND: Despite stroke's high prevalence in the elderly, intravenous thrombolysis is licensed in Europe only for patients younger than 80 years old. We aimed to compare the functional outcomes and complication rates in patients older versus younger than 80 years old treated with intravenous thrombolysis. METHODS: A retrospective observational study of patients who received intravenous thrombolysis in a stro...
Successful Thrombolysis despite Having an Incidental Unruptured Cerebral Aneurysm
Briosa e Gala, D; Almeida, A; Monteiro, N; Paiva Nunes, A; Ferreira, P; Mendonça, N; Amaral-Silva, APurpose. To report a case of successful thrombolysis performed in a patient with an incidental unruptured intracranial aneurysm and review the literature. Case Report. Patient admitted for ischemic stroke due to left posterior cerebral artery occlusion, with an incidental right middle cerebral artery aneurysm, who underwent treatment with tissue plasminogen activator (rtPA) resulting in clinical improvement wit...
Predicting Outcome after Cardiopulmonary Arrest in Therapeutic Hypothermia Pati...
Maia, B; Roque, R; Amaral-Silva, A; Lourenço, S; Bento, L; Alcântara, JINTRODUCTION: Predicting outcome in comatose survivors of cardiac arrest is based on data validated by guidelines that were established before the era of therapeutic hypothermia. We sought to evaluate the predictive value of clinical, electrophysiological and imaging data on patients submitted to therapeutic hypothermia. MATERIALS AND METHODS: A retrospective analysis of consecutive patients receiving therapeut...