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Uptake studies in rat Peyer's patches, cytotoxicity and release studies of algi...

Borges, Olga; Cordeiro-da-Silva, Anabela; Romeijn, Stefan G.; Amidi, Maryam; Sousa, Adriano de; Borchard, Gerrit; Junginger, Hans E.

The design of particulate vaccine delivery systems, particularly for mucosal surfaces, has been a focus of interest in recent years. In this context, we have previously described the development and the characterization of a new nanosized delivery system, consisting of a model antigen adsorbed to chitosan particles and coated with sodium alginate. In the present work the ovalbumin release profiles from these co...


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