5 documents found, page 1 of 1
Minimum clinical utility standards for wearable seizure detectors: a simulation...
Goldenholz, Daniel M.; Karoly, Philippa J.; Viana, Pedro; Nurse, Ewan; Loddenkemper, Tobias; Schulze‐Bonhage, Andreas; Vieluf, Solveig; Bruno, ElisaObjective: Epilepsy management employs self-reported seizure diaries, despite evidence of seizure underreporting. Wearable and implantable seizure detection devices are now becoming more widely available. There are no clear guidelines about what levels of accuracy are sufficient. This study aimed to simulate clinical use cases and identify the necessary level of accuracy for each. Methods: Using a realistic sei...
Seizure forecasting using minimally invasive, ultra‐long‐term subcutaneous elec...
Viana, Pedro; Pal Attia, Tal; Nasseri, Mona; Duun‐Henriksen, Jonas; Biondi, Andrea; Winston, Joel S.; Martins, Isabel Pavão; Nurse, Ewan S.Objective: One of the most disabling aspects of living with chronic epilepsy is the unpredictability of seizures. Cumulative research in the past decades has advanced our understanding of the dynamics of seizure risk. Technological advances have recently made it possible to record pertinent biological signals, including electroencephalogram (EEG), continuously. We aimed to assess whether patient-specific seizur...
Non-invasive wearable seizure detection using long–short-term memory networks w...
Nasseri, Mona; Pal Attia, Tal; Joseph, Boney; Gregg, Nicholas M.; Nurse, Ewan S.; Viana, Pedro; Schulze-Bonhage, Andreas; Dümpelmann, MatthiasObjective. The detection of seizures using wearable devices would improve epilepsy management, but reliable detection of seizures in an ambulatory environment remains challenging, and current studies lack concurrent validation of seizures using electroencephalography (EEG) data. Approach. An adaptively trained long–short-term memory deep neural network was developed and trained using a modest number of seizure ...
Seizure diaries and forecasting with wearables: epilepsy monitoring outside the...
Brinkmann, Benjamin H.; Karoly, Philippa J.; Nurse, Ewan S.; Dumanis, Sonya B.; Nasseri, Mona; Viana, Pedro; Schulze-Bonhage, AndreasIt is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by infrequent seizures based on patient or caregiver reports and limited duration clinical testing. The poor reliability of self-reported seizure diaries for many people with epilepsy is well-established, but these records remain necessary in clinical care and therapeutic studies. A number of wearable devices have emerged...
230 days of ultra long‐term subcutaneous EEG : seizure cycle analysis and compa...
Viana, Pedro; Duun‐Henriksen, Jonas; Glasstëter, Martin; Dümpelmann, Matthias; Nurse, Ewan S.; Martins, Isabel Pavão; Dumanis, Sonya B.We describe the longest period of subcutaneous EEG (sqEEG) monitoring to date, in a 35-year-old female with refractory epilepsy. Over 230 days, 4791/5520 h of sqEEG were recorded (86%, mean 20.8 [IQR 3.9] hours/day). Using an electronic diary, the patient reported 22 seizures, while automatically-assisted visual sqEEG review detected 32 seizures. There was substantial agreement between days of reported and reco...