53 documents found, page 1 of 6
A case of equine multicentric lymphoma: Clinical, microscopical, and molecular ...
Silva, GF; Ribeiro, TE; Cunha, R; Salas, PB; Guimarães, T; Ribeiro, MR; Barros, G; Carvalho, F; Mesquita, JR; Amorim, IBackground: Although relatively uncommon, lymphoma is the most prevalent haematopoietic neoplasia in horses, and multicentric lymphoma remains the most common presentation of the disease. The pathogenesis of equine lymphoma is still poorly understood and the diagnosis is usually confirmed at an advanced stage of the disease, compromising the prognosis. This study investigated the clinical, pathological, and mol...
Paving the way for a non‐antibiotic and microbiota friendly therapy for Helicob...
Seabra, CL; Pinho, AS; Nunes, C; Amorim, I; Pedro, N; Henriques, P; Monteiro, C; Gomes, J; Machado, C; Gartner, F; Pereira, L; Reis, S; Reis, CABackground: The World Health Organization has identified Helicobacter pylori, a Gram-negative bacterium responsible for several gastric disorders, as one of the pathogenic bacteria that requires newer non-antibiotic approaches for its management. We previously demonstrated that nanostructured lipid carriers (NLC) loaded with docosahexaenoic acid (DHA-NLC)have excellent in vitro performance against H. pylori. Ma...
Comparative epidemiological study of breast cancer in humans and canine mammary...
Carvalho, PT; Niza-Ribeiro, J; Amorim, I; Queiroga, F; Severo, M; Ribeiro, AI; Pinello, KDogs spontaneously develop mammary gland tumors (MGT) and exhibit striking similarities in clinical and epidemiological characteristics to human breast cancer (HBC). Descriptive and comparative analysis of HBC and canine MGT with a focus on evaluating similarities and geographical distribution were the aims of this study. HBC cases were obtained from North Regional Oncological Registry (RORENO) (2010–2015) and ...
Correspondence: The One Health concept applied to dirofilariasis-a zoonotic dis...
Gomes-de-Sá; Barradas, P; Amorim, I; Cardoso, L; Mesquita, Jn/a
Molecular Detection of Metronidazole and Tetracycline Resistance Genes in Helic...
Nunes, FC; Taillieu, E; Mateus, TL; Teixeira, S; Haesebrouck, F; Amorim, IAntimicrobial resistance is a major public health concern. The aim of this study was to assess the presence of antibiotic resistance genes, previously reported in Helicobacter pylori, in gastric samples of 36 pigs, in which DNA of H. pylori-like organisms had been detected. Based on PCR and sequencing analysis, two samples were positive for the 16S rRNA mutation gene, conferring tetracycline resistance, and one...
Assessment of the circulation of Dirofilaria immitis in dogs from northern Port...
Gomes-de-Sá, S; Santos-Silva, S; Moreira, AS; Barradas, PF; Amorim, I; Cardoso, L; Mesquita, JRDirofilariasis is a vector-borne disease frequent in many countries. Not only infected dogs, but also cats and wild canids (including wolves and foxes), represent important sources of infection for mosquitoes, which are the pathogen vectors. The disease is endemic in Mediterranean countries with increasing incidence in Italy, France, Greece and Spain, but limited epidemiological data is available from Portugal ...
E-cadherin Expression in Canine Gastric Carcinomas: Association with Clinicopat...
Flores, AR; Rêma, A; Mesquita, JR; Taulescu, M; Seixas, F; Gärtner, F; Amorim, IE-cadherin (E-cad) is a cell-adhesion molecule known for its tumor-invasion suppressor function. E-cad expression was examined immunohistochemically in a series of canine tissue samples, including normal gastric mucosa (NGM; n = 3), gastric carcinomas (GC; n = 33), adjacent nonneoplastic mucosa (NNM; n = 32), neoplastic emboli (n = 16) and metastatic lesions (n = 9). The relationship between E-cad expression an...
Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs a...
Cortez Nunes, F; Letra, Mateus, T; Taillieu, E; Teixeira, S; Carolino, N; Rema, A; De Bruyckere, S; Gärtner, F; Haesebrouck, F; Amorim, IBesides Helicobacter pylori, a Gram-negative bacterium that may cause gastric disorders in humans, non-Helicobacter pylori helicobacters (NHPH) may also colonize the stomach of humans and animals. In pigs, H. suis can induce gastritis and may play a role in gastric ulcer disease, possibly in association with Fusobacterium gastrosuis. In the present study, gastric samples from 71 slaughtered pigs and 14 hunted f...
De Novo Assembly of the Dirofilaria immitis Genome by Long-Read Nanopore-Based ...
Gomes-de-Sá, S; Barradas, P; Queirós-Reis, L; Matas, IM; Amorim, I; Cardoso, L; Muñoz-Mérida, A; Mesquita, JRDirofilaria immitis is a zoonotic parasitic nematode that infects domestic and wild canids, among its vertebrate hosts. The genetic analysis of D. immitis nowadays transcends the need for genetic taxonomy of nematodes, such as the study of resistance to macrocyclic lactone. We expanded the use of long-read nanopore-based sequencing technology on nematodes by performing genomic de novo assembly of a D. immitis s...
Dirofilaria immitis antigenemia and microfilaremia in Iberian wolves and red fo...
Gomes-de-Sá, S; Santos-Silva, S; Moreira, AS; Barradas, PF; Amorim, I; Cardoso, L; Mesquita, JRBackground: Dirofilaria immitis is a parasitic nematode endemic in the Mediterranean countries, which causes cardiopulmonary dirofilariosis in wild and domestic animals. Despite being recognized hosts of D. immitis, wild carnivores such as wolves and foxes are frequently disregarded when considering a potential role in the transmission of these zoonotic nematodes. In Portugal, studies available regarding D. imm...