Funding Information: This review was funded by the Portuguese Foundation for Science and Technology (FCT), projects UI/00772 and SFRH/122894/2016. Publisher Copyright: © 2025 by the authors.; Canine monocytic ehrlichiosis (CME) is a highly infectious disease with zoonotic potential. Ehrlichia canis, the causative agent, is primarily transmitted by Rhipicephalus sanguineus. Tick infestation and tick-borne diseas...