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Endometrial serous adenocarcinoma: A case study

Luís, A; Vieira, D; Tavares, V; Roque, R; Mendonça, P; André, S

Endometrial adenocarcinoma is one of the most frequent malignant neoplasms of the female genital tract in Western Europe and North America. More than 90% of cases occur in women over 50 years-old, however, 4% of cases occur before 40 years-old. The present clinical case concerns a 74 years-old woman with blood loss, a vaginal ulcerated lesion, and an enlarged uterus. She consequently underwent a colpocytology, ...

Date: 2025   |   Origin: Citotech Online - Case Review

Cystic Adenoid Carcinoma of Bartholin’s Gland: Case Report of a Distant Metastasis

Silva, I; Santos, I; Tavares, V; Roque, R; André, S; Mendonça, P

Adenoid cystic carcinoma in Bartholin’s gland is a rare malignant gynecologic tumor that appears as a solid lesion, movable and painful, with slow growth. It is a tumor associated with frequent local recurrence and metastasis, which can occur several years after the primary lesion. The clinical diagnosis includes cystic lesion or abscess. However, it has a very particular morphologic presentation, which allows ...

Date: 2025   |   Origin: Citotech Online - Case Review

Granular cell tumor of the breast: correlations between imaging and pathology f...

Abreu, N; Filipe, J; André, S; Marques, JC

OBJECTIVE: To review the imaging features of granular cell tumors of the breast (on mammography, ultrasound, and magnetic resonance imaging), establishing a pathological correlation, in order to familiarize radiologists with this entity and make them aware of the differential diagnoses, other than malignancy, of lesions with spiculated margins. MATERIALS AND METHODS: We reviewed the medical records (from a clin...


COPD and Cardiovascular Disease

André, S; Conde, B; Fragoso, E; Boléo-Tomé, JP; Areias, V; Cardoso, J

COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020. COPD and cardiac comorbidities are frequently associated. They share common risk factors, pathophysiological processes, signs and symptoms, and act synergistically as negative prognostic factors. Cardiac disease ...


COPD and Cardiovascular Disease.

André, S; Conde, B; Fragoso, E; Boléo-Tomé, JP; Areias, V; Cardoso, J; GI DPOC-Grupo de Interesse na Doença Pulmonar Obstrutiva Crónica

COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020. COPD and cardiac comorbidities are frequently associated. They share common risk factors, pathophysiological processes, signs and symptoms, and act synergistically as negative prognostic factors. Cardiac disease ...


Prevalence of Late-Onset Pompe Disease in Portuguese Patients with Diaphragmati...

Guimarães, MJ; Winck, JC; Conde, B; Mineiro, A; Raposo, M; Moita, J; Marinho, A; Silva, JM; Pires, N; André, S; Loureiro, C

Pompe disease is a rare autosomal recessive neuromuscular disorder caused by acid α-glucosidase enzyme (GAA) deficiency and divided into two distinct variants, infantile- and late-onset. The late-onset variant is characterized by a spectrum of phenotypic variation that may range from asymptomatic, to reduced muscle strength and/or diaphragmatic paralysis. Since muscle strength loss is characteristic of several ...


Understanding COPD: a vision on phenotypes, comorbidities and treatment approach.

Fragoso, E; André, S; Boléo-Tomé, JP; Areias, V; Munhá, J; Cardoso, J; GI DPOC-Grupo de Interesse na Doença Pulmonar Obstrutiva Crónica

Chronic Obstructive Pulmonary Disease (COPD) phenotypes have become increasingly recognized as important for grouping patients with similar presentation and/or behavior, within the heterogeneity of the disease. The primary aim of identifying phenotypes is to provide patients with the best health care possible, tailoring the therapeutic approach to each patient. However, the identification of specific phenotypes...


Understanding COPD: A Vision on Phenotypes, Comorbidities and Treatment Approach

Fragoso, E; André, S; Boleo-Tomé, JP; Areias, V; Munhá, J; Cardoso, J

Chronic Obstructive Pulmonary Disease (COPD) phenotypes have become increasingly recognized as important for grouping patients with similar presentation and/or behavior, within the heterogeneity of the disease. The primary aim of identifying phenotypes is to provide patients with the best health care possible, tailoring the therapeutic approach to each patient. However, the identification of specific phenotypes...


A rare case of hyperandrogenism: bilateral Leydig cell tumor of the ovary.

Marcelino, M; Nobre, Ema; Conceição, J; Lopes, L; Vilar, H; França Martins, M; Carvalho, A; André, S; Horta, A; De Castro, J Jácome

The androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this type of lesion and it is usually benign, small and unilateral.A 67 year old woman was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman-Gallwey) and male type alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testo...

Date: 2010   |   Origin: Acta Médica Portuguesa

Pneumonia eosinofílica crónica idiopática: A propósito de um caso clínico

Valente, C; André, S; Catarino, A; Loureiro, M; Baganha, MF

The eosinophilic pneumonias are a heterogeneous group of pulmonary disorders, which may compromise only the air ways, the pulmonary parenchyma, or both, characterised by alveolar eosinophils and infiltration of pulmonary tissue, with or without peripheral blood eosinophilia. Idiopathic Chronic Eosinophilic Pneumonia (ICEP), detailed description was by Carrington in 1969, is a rare eosinophilic lung disease, of ...


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