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Prolonged maternal separation induces undernutrition and systemic inflammation ...

Figueiredo, Ítalo Leite; Frota, Priscila B.; Cunha, Davi G. da; Raposo, Ramon da Silva; Canuto, Kildere M.; Andrade, Geanne M. de; Sousa, Nuno

Objective: Prolonged maternal separation (PMS) in the first 2 wk of life has been associated with poor growth with lasting effects in brain structure and function. This study aimed to investigate whether PMS-induced undernutrition could cause systemic inflammation and changes in nutrition-related hormonal levels, affecting hippocampal structure and neurotransmission in C57BL/6J suckling mice. Methods: This stud...


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