6 documents found, page 1 of 1

Variantes genéticas do gene IFITM3 revelam um potencial modificador da gravidad...

As epidemias de gripe representam um sério problema de saúde pública com elevados custos económicos. Foi sugerido que um dos alelos do gene IFITM3 (rs12252-C) constitui um impor tante fator de risco de base populacional para as formas graves da gripe por infeção pelo vírus A(H1N1)pdm09. Analisámos variantes do IFITM3 associadas à gravidade da doença em doentes por tugueses (n=41). Foram identificados sete SNPs ...

Population genetics of IFITM3 in Portugal and Central Africa reveals a potentia...

Influenza epidemics are a serious global public health and economic problem. The IFITM3 allele (rs12252-C) was suggested as a population-based genetic risk factor for severe influenza virus infection by A(H1N1)pdm09. We analyzed the population genetics of IFITM3 variants in the Portuguese general population (n = 200) and Central Africans (largely Angolan) (n = 148) as well as its association to influenza severi...

Association between chronic stress and immune response to influenza vaccine in ...

A B S T R A C T - Introduction: Chronic stress can influence immune response to vaccines. Healthcare workersare exposed to stressors and biological hazards, the health effects of which may be preventedthrough vaccination.Objectives: This study aims to evaluate the association between stress in nurses and: (1)insufficient response to influenza vaccine, assessed one month after vaccination (T1); (2)the drop in ha...

Perfil de suscetibilidade do vírus influenza aos antivirais específicos para a ...

Outbreak of acute respiratory infection among infants in Lisbon, Portugal, caus...

Human adenoviruses (AdVs) typically cause mild illnesses in otherwise healthy hosts. We investigated a pediatric outbreak of acute respiratory infection with fatal outcomes that occurred in Lisbon, Portugal, in 2004. Biological specimens were collected from 83 children attending two nurseries, a kinesiotherapy clinic, and the household of a nanny. Adenovirus infection was confirmed in 48 children by PCR and vir...

Antiviral drug profile of seasonal influenza viruses circulating in Portugal fr...

A research project on antiviral drug resistance of influenza viruses circulating in Portugal has been carried out since 2007. Here, the first results obtained regarding the evaluation of susceptibility to amantadine and oseltamivir are presented. Information about antiviral prescription and exposure was available through the National Influenza Surveillance Programme. Amantadine susceptibility was evaluated by p...