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Development of a cellprofiler pipeline to evaluate adipocyte differentiation

Andrade, João; Torres, Sílvia; Coelho, Pedro; Coelho, Pedro

Obesity is a complex chronic disease characterized by excessive body fat accumulation, with increasingly prevalence worldwide, burdening individuals and healthcare systems, thus urgent research is needed. (1,2) Adipocytes, the major cellular component of adipose tissue, are cells vastly used by the scientific community for in vitro studies of obesity. (3) Oil red O (ORO) staining and quantification is widely us...


Chemical composition, biocompatibility, and anti-Candida albicans activity of S...

Andrade, João; Almeida-Apolonio, Adriana; Dantas, Fabiana; Nogueira, Cláudio; Pinto, Luciano; Moraes, Carlos; Fernandes, Liliana Sousa

Recurrent vulvovaginal candidiasis (RVVC), predominantly caused by Candida albicans, represents a global health issue, particularly in developing regions. This study explores the antifungal potential of aqueous leaf extract of Schinus weinmanniifolia Mart. ex Engl., a native Latin American plant. The extract was evaluated for phytochemical composition, antifungal efficacy, and safety profile. Phytochemical anal...


A Novel Biomarker of Compensatory Recruitment of Face Emotional Imagery Network...

Simões, Marco; Monteiro, Raquel; Andrade, João; Mouga, Susana; França, Felipe; Oliveira, Guiomar; Carvalho, Paulo; Castelo-Branco, Miguel

Imagery of facial expressions in Autism Spectrum Disorder (ASD) is likely impaired but has been very difficult to capture at a neurophysiological level. We developed an approach that allowed to directly link observation of emotional expressions and imagery in ASD, and to derive biomarkers that are able to classify abnormal imagery in ASD. To provide a handle between perception and action imagery cycles it is im...


Design Space Exploration of LDPC Decoders Using High-Level Synthesis

Andrade, João; George, Nithin; Karras, Kimon; Novo, David; Prata, Frederico; Sousa, Leonel; Ienne, Paolo; Falcao, Gabriel; Silva, Vitor

Today, high-level synthesis (HLS) tools are being touted as a means to perform rapid prototyping and shortening the long development cycles needed to produce hardware designs in register transfer level (RTL). In this paper, we attempt to verify this claim by testing the productivity bene ts offered by current HLS tools by using them to develop one of the most important and complex processing blocks of modern so...


Separability of motor imagery of the self from interpretation of motor intentio...

Andrade, João; Cecílio, José; Simões, Marco; Sales, Francisco; Castelo-Branco, Miguel

Background: We aimed to investigate the separability of the neural correlates of 2 types of motor imagery, self and third person (actions owned by the participant himself vs. another individual). If possible this would allow for the development of BCI interfaces to train disorders of action and intention understanding beyond simple imitation, such as autism. Methods: We used EEG recordings from 20 healthy parti...





A Survey on Programmable LDPC Decoders

Andrade, João; Falcão, Gabriel; Silva, Vitor; Sousa, Leonel

Low-density parity-check (LDPC) block codes are popular forward error correction schemes due to their capacity-approaching characteristics. However, the realization of LDPC decoders that meet both low latency and high throughput is not a trivial challenge. Usually, this has been solved with the ASIC and FPGA technology that enables meeting the decoder design constraints. But the rise of parallel architectures, ...


BCI Framework Based on Games to Teach People With Cognitive and Motor Limitations

Cecílio, José; Andrade, João; Martins, Pedro; Castelo Branco, Miguel; Furtado, Pedro

Nowadays, Human-Computer Interaction (HCI) systems e.g. keyboard, mouse and touch screen are frequently used by anyone. However, those ways to interact with computers may be not suitable for disabled persons. Brain-Computer Interface (BCI) is an HCI system which can be used as an alternative for these persons. This approach allows operating a computer using only the brain signals, for instance, imagine a situat...


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