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Hemodynamic Predictors And Changes During Carotid Endarterectomy Under Regional...

Silva, Vera A.; D. Gamas, Luís; Pereira-Macedo, Juliana; Carreira, Mariana; Myrcha, Piotr; Andrade, José P.; L. Moreira, André; Rocha-Neves, João

Objectives: Carotid endarterectomy (CEA) is the standard treatment for carotid stenosis, but it can lead to cerebral hypoperfusion and hemodynamic stroke. Regional anesthesia (RA) and light sedation allow continuous monitoring of intraoperative neurological function. However, the relationship between perioperative hemodynamic management and neurological dysfunction has yet to be thoroughly investigated. This st...


R2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomy

Quesado, João; Dias, Lara; Pereira-Macedo, Juliana; Duarte-Gamas, Luís; Khairy, Ahmed; Pinheiro, Marina; Reis, Pedro; Andrade, José P.

Background: R2CHA2DS2-VA score has been used to predict short and long-term outcomes in many cardiovascular diseases. This study aims to validate the R2CHA2DS2-VA score as a long-term major adverse cardiovascular events (MACE) predictor after carotid endarterectomy (CEA). Secondary outcomes were also assessed regarding the incidence of all-cause mortality, acute myocardial infarction (AMI), major adverse limb e...


Mean platelet volume predicts restenosis after carotid endarterectomy

Pereira-Neves, António; Saramago, Sean; Duarte-Gamas, Luís; Domingues-Monteiro, Diogo; Fragão-Marques, Mariana; Marques-Vieira, Mário; Andrade, José P.

Background: Carotid restenosis following carotid endarterectomy (CEA) has a cumulative risk at 5-years up to 32%, which may impact the well-being of patients following CEA. Haematological parameters in the standard complete blood cell count (CBC) are emerging as potential biomarkers, but their application in CEA is scarce. The primary aim of this study was to investigate haematological markers for restenosis fo...


Contralateral carotid stenosis is a predictor of long-term adverse events in ca...

Moreira, Rita; Duarte-Gamas, Luís; Pereira-Macedo, Juliana; Pereira-Neves, António; Domingues-Monteiro, Diogo; Jácome, Filipa; Andrade, José P.

Contralateral carotid stenosis (cICS) has been described as a perioperative predictor of mortality after carotid endarterectomy (CEA). However, its predictive value on long-term cardiovascular events remains controversial. The study aims to assess the potential role of cICS as a long-term predictor of major adverse cardiovascular events (MACE) in patients who underwent CEA. From January 2012 to July 2020, patie...


Control of zootechnology leads to improved cuttlefish (Sepia officinalis, L.) r...

Capaz, Juan C.; Hernández-Brooke, Daniel; Balvet, Safia; Couto, Ana T.; Alves, Alexandra C.; Gonçalves, Rui A.; Frias, Paulo A.; Andrade, José P.

Cephalopods are gaining momentum as an alternate group for aquaculture species diversification, not only because they are a good food source (highly appreciated in some worldwide markets) but they also have the potential to quickly reach a market size. However, there are some bottlenecks impeding the transition of culture technology from the laboratory to industry. One is related to control over reproduction in...


Computational analysis of the SARS-CoV-2 and other viruses based on the Kolmogo...

Machado, J. A. Tenreiro; Rocha-Neves, João M.; Andrade, José P.

This paper tackles the information of 133 RNA viruses available in public databases under the light of several mathematical and computational tools. First, the formal concepts of distance metrics, Kolmogorov complexity and Shannon information are recalled. Second, the computational tools available presently for tackling and visualizing patterns embedded in datasets, such as the hierarchical clustering and the m...


Multidimensional scaling analysis of virus diseases

Lopes, António M.; Andrade, José P.; Machado, J.A.Tenreiro

Background and Objective: Viruses are infectious agents that replicate inside organisms and reveal a plethora of distinct characteristics.Viral infections spread in many ways, but often have devastating consequences and represent a huge danger for public health. It is important to design statistical and computational techniques capable of handling the available data and highlighting the most important features....


Ageing of swordfish, Xiphias gladius Linnaeus, 1758, from the Azores, using sag...

Esteves, Eduardo; Simões, Patrícia; Silva, Hélder M.; Andrade, José P.

Determinaram-se as idades de espadartes, Xiphias gladius Linnaeus 1758, capturados nos Açores a partir de três estruturas ósseas diferentes (sagittae esquerdos, 2º espinhos da barbatana anal e vértebras; n=155). Comparam-se estas estruturas em termos de: facilidade de amostragem e processamento; leitura e interpretação de marcas de idade e repetibilidade das estimações de idade. Obtiveram-se relações lineares, ...


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