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Screening of antimicrobial metabolite yeast isolates derived biome Ceará agains...

Andrade Neto, João Batista de; Silva, Cecília R. da; Nascimento, Francisca Bruna Stefany Aires do; Sampaio, Letícia Serpa; Silva, Anderson R. da

Antimicrobials benefited the history of medicine by revolutionizing the treatment of infectious diseases. However, its consequent and continuous use has led to the emergence of microorganisms which once were considered safe, but have become feared as potentially lethal pathogens (Bowler et al., 2012). Staphylococcus aureus infections are highlighted for being a major cause of systemic infections, and for being ...

Date: 2016   |   Origin: Oasisbr

Effects of piperonal nitro derivatives on candida species : antifungal activity...

Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Freitas, Daniel Domingues

Recently, there has been a significant increase in invasive fungal infections, the treatment of which is limited to a quite small number of antifungal drugs. Natural products represent an important source of antifungal agents, mainly because of their natural coexistence with fungi present in each biome. Derivatives or semi-synthetic products can be used to optimize the pharmacological profile of natural product...

Date: 2016   |   Origin: Oasisbr

Berberine antifungal activity in fluconazole-resistant pathogenic yeasts : acti...

Silva, Anderson Ramos da; Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Silva, Rose Anny Costa

The incidence of fungal infections and, in particular, the incidence of fungal antibiotic resistance, which is associated with bio- film formation, have significantly increased, contributing to morbidity and mortality. Thus, new therapeutic strategies need to be developed. In this context, natural products have emerged as a major source of possible antifungal agents. Berberine is a pro- toberberine-type isoquin...

Date: 2016   |   Origin: Oasisbr

Evaluation of synergistic effect of kaurenoic acid derivatives with fluconazole...

Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Sampaio, Letícia Serpa

Candida species are the fourth most common cause of nosocomial bloodstream infections in the United States and the fifth to tenth most common causative pathogen in European studies Although C. albicans remains the most common fungal isolate recovered from blood, recent reports indicate a trend towards an increasing prevalence of infections caused by species of Candida other than C. albicans which are associated...

Date: 2016   |   Origin: Oasisbr

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