Patients with reflux esophagitis have lower thickness and functional fai lure of the crural diaphragm (CD ), a fact that supports the possible ex istence of a skeletal muscle deficiency in patients with Gastroesophageal Reflux Disease GERD )). In addition, the relationship between Helicobacter pylori and GERD presents some divergences between the studies, requiring a greater number of studies capable of clarify...
Introduction: Chagas’ disease (DC) is a parasite caused by the infectious agent Trypanosoma cruzi. In Brazil, the specific treatment of CD is performed with Benzonidazole (Bz), which due to its toxicity, can lead to the appearance of several adverse reactions to patients who use it. Therefore, there is a certain concern in evaluating the patient before starting the use of Bz, in order to verify possible hematol...
Abstract: Background: Treatment with benzonidazole in the chronic phase of Chagas disease remains controversial. This study is aimed at evaluating the effectiveness of chemotherapy with benzonidazole in chronic Chagas disease using serological and electrocardiographic analysis. Method: Historical prospective study with electrocardiographic and serological monitoring by enzyme immunoassay (ELISA) and indirect im...
Introduction: The role of trypanocidal therapy in the chronic phase of Chagas disease remains controversial. Methods: A total of 13 patients with chronic Chagas disease were treated with benznidazole (5mg/kg/day/60 days) and surveyed via antibody measurement and conventional electrocardiogram over the course of 4 years. Results: The antibody titers were signifi cantly reduced after 4 years (p<0.05). Most of the...
Chagas disease (CD) is a pathology of endemic nature, caused by the protozoan Trypanosoma cruzi, with pronounced relevance between heart disease. It was officially described in 1909 and even after more than a century of its discovery is still a public health problem. The aim of this study was to evaluate the effectiveness of chemotherapy with Benznidazole (Bz) in patients with chronic Chagas disease by serologi...