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Síntese e avaliação da atividade antimicrobiana de furanonas halogenadas e de c...

Barbosa, Luiz C. A.; Maltha, Célia R. A.; Demuner, Antônio J.; Pinheiro, Patrícia F.; Varejão, Jodieh O. S.; Montanari, Ricardo M.; Andrade, Nélio J.

Considering the broad spectrum of biological activity of gamma-butyrolactone derivatives, we presented the synthesis of 3,4-dihalo-5-arylidenefuran-2(5H)-ones (17-21) and analogues (24-28) of the natural product nostoclide (7,8). Furanones 17-21 were synthesized from the condensation of aromatic aldehydes with lactones 14 and 15, that were obtained from mucobromic and mucochloric acids. Lactone 15 was converted...

Date: 2019   |   Origin: Oasisbr

Chemical composition and antibacterial activities from the essential oils of my...

Silva, Cleber J.; Barbosa, Luiz C. A.; Demuner, Antonio J.; Montanari, Ricardo M.; Pinheiro, Antônio L.; Dias, Iara; Andrade, Nélio J.

The essential oils of seven Myrtaceae species were investigated for its chemical composition and antibacterial activity. The volatile oils were characterized by a high content of monoterpenoids of which 1,8-cineole (88.0, 65.0 and 77.0% for Melaleuca hypericifolia, Callistemon viminalis and Callistemon citrinus respectively), terpinen-4-ol (47.0 and 49.8% for Melaleuca thymifolia and Callistemon polandii respec...

Date: 2019   |   Origin: Oasisbr

Chemical composition and antibacterial activity of essential oils from verbenac...

Montanari, Ricardo M.; Barbosa, Luiz C. A.; Demuner, Antonio J.; Silva, Cleber J.; Carvalho, Larissa S.; Andrade, Nélio J.

Volatile oils from the leaves of Verbenaceae species Aloysia virgata, Lantana camara, Lantana trifolia, Lantana montevidensis, Lippia brasiliensis and Lippia sericea were investigated for its chemical composition and antibacterial activity. The volatile oils were characterized by a high content of sesquiterpenes of which (E)-caryophyllene (10-35%), germacrene-D (5-46%) and bicyclogermacrene (7-17%) were the maj...

Date: 2018   |   Origin: Oasisbr

Thermodynamic study of colorimetric transitions in polydiacetylene vesicles ind...

Pires, Ana Clarissa S.; Soares, Nilda de Fátima F.; Silva, Luis Henrique M. da; Silva, Maria C. Hespanhol da; Mageste, Aparecida B.; Soares, Rêmili F.

We report the synthesis of 10,12-pentacosadyinoic acid (PCDA) and PCDA + cholesterol (CHO) + sphingomyelin (SPH) vesicles dispersed in water and the determination of their colorimetric response induced by small amount of organic solvents. In the absence of solvent, PCDA and PCDA/CHO/SPH vesicles showed an intense blue color. The addition of CHCl 3 , CH 2 Cl 2 , and CCl 4 caused a colorimetric transition (CT) in...

Date: 2018   |   Origin: Oasisbr

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