3 documents found, page 1 of 1
Laccase affects the rate of Cryptococcus neoformans nonlytic exocytosis from ma...
Frazão, Stefânia de Oliveira; Sousa, Herdson Renney de; Silva, Lenise Gonçalves da; Folha, Jéssica dos Santos; Gorgonha, Kaio César de MeloNonlytic exocytosis is a process in which previously ingested microbes are expelled from host phagocytes with the concomitant survival of both cell types. This process has been observed in the interaction of Cryptococcus spp. and other fungal cells with phagocytes as distant as mammalian, bird, and fish macrophages and ameboid predators. Despite a great amount of research dedicated to unraveling this process, t...
Molecular and cellular biomarkers of COVID-19 prognosis : protocol for the pros...
Kurizky, Patricia Shu; Nóbrega, Otávio T.; Soares, Alexandre Anderson de Sousa Munhoz; Aires, Rodrigo Barbosa; Albuquerque, Cleandro Pires deBackground: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...
The stress responsive and morphologically regulated HSP90 gene from Paracoccidi...
Matos, Larissa Fernandes; Andrade, Rosângela Vieira de; Dantas, Alessandra da Silva; Andrade, Patrícia Albuquerque de; Arraes, Barbosa Monteiro ArraesBackground Paracoccidioides brasiliensis is a dimorphic fungus that causes the most prevalent systemic mycosis in Latin America. The response to heat shock is involved in pathogenesis, as this pathogen switches from mycelium to yeast forms in a temperature dependent fashion that is essential to establish infection. HSP90 is a molecular chaperone that helps in the folding and stabilization of selected polypeptid...