11 documents found, page 1 of 2
GLP-1 Increases Circulating Leptin Levels in Truncal Vagotomized Rats
Morais, T; Pereira, SS; Andrade, S; Neves, D; Guimaraes, M; Nora, M; Carreira, MC; Casanueva, FF; Monteiro, MPGLP-1 is a gastro-intestinal hormone acting within the gut/brain axis for energy balance regulation. We aimed to evaluate the role of the vagus nerve in whole-body energy homeostasis and in mediating GLP-1 effects. For this, rats submitted to truncal vagotomy and sham-operated controls underwent a comprehensive evaluation, including eating behavior, body weight, percentage of white (WAT) and brown adipose tissu...
Visceral Adipose Tissue Bioenergetics Varies According to Individuals' Obesity ...
Topete, MV; Andrade, S; Bernardino, RL; Guimaraes, M; Pereira, AM; Oliveira, SB; Costa, MM; Nora, M; Monteiro, MP; Pereira, SSObesity is associated with complex adipose tissue energy metabolism remodeling. Whether AT metabolic reprogramming differs according to body mass index (BMI) and across different obesity classes is unknown. This study's purpose was to evaluate and compare bioenergetics and energy substrate preference of visceral adipose tissue (VAT) pertaining to individuals with obesity class 2 and class 3. VAT obtained from p...
Establishing a link between endothelial cell metabolism and vascular behaviour ...
Silva, C; Sampaio-Pinto, V; Andrade, S; Rodrigues, I; Costa, R; Guerreiro, SG; Carvalho, E; Pinto-do-Ó, P; Nascimento, DS; Soares, RBackground/Aims: Vascular complications contribute significantly to the extensive morbidity and mortality rates observed in people with diabetes. Despite well known that the diabetic kidney and heart exhibit imbalanced angiogenesis, the mechanisms implicated in this angiogenic paradox remain unknown. In this study, we examined the angiogenic and metabolic gene expression profile (GEP) of endothelial cells (ECs)...
Prostate cancer cells are able to interact with surrounding adipocytes inducing...
Moreira, A; Pereira, S S; Andrade, S; Rodrigues, A; Santos, M; Morais, T; Gouveia, Alexandra; Monteiro, M P
Dabigatran-Related Nephropathy in a Patient with Undiagnosed IgA Nephropathy
Escoli, R; Santos, P; Andrade, S; Carvalho, FDabigatran is a direct thrombin inhibitor used as an alternative to warfarin for long term anticoagulation. Warfarin-related nephropathy is an increasingly recognized entity, but recent evidence suggests that dabigatran can cause a WRN-like syndrome. We describe a case of a biopsy-proven anticoagulant nephropathy related to dabigatran in a patient with IgA nephropathy and propose that, despite the base glomerul...
Avaliação da prevalência e caracterização da rinossinusite nos cuidados de saúd...
Barros, E; Silva, A; Vieira, A; André, C; Silva, D; Prata, J; Ferreira, J; Santos, M; Gonçalves, P; Leiria, E; Gonçalves, N; Andrade, SAbstract: To determine RS prevalence, diagnosed at the Portuguese Primary Health Care Centres (PHCC), and to assess diagnostic and treatment practices. Study Design: Epidemiologic, cross-sectional study. Material and Methods:A cohort of subjects attending general practice medical appointments, in selected PHCC, was evaluated. Results: Between May/2008 and June/2009, 1,201 subjects were included with a mean age ...
Avaliação da Prevalência e Caracterização da Rinossinusite nos Cuidados de Saúd...
Barros, E; Silva, A; Sousa Vieira, A; André, C; Silva, D; Branquinho Prata, J; Pinto Ferreira, J; Santos, M; Gonçalves, P; Leiria, E; Gonçalves, NObjectivos: Determinar a prevalência da rinossinusite (RS) diagnosticada nos Centros de Saúde (CS) portugueses, aferindo formas de apresentação e tratamento desta patologia. Desenho do Estudo: Estudo epidemiológico, transversal. Material e Métodos: Entre Maio/2008 e Junho/2009 avaliouse uma coorte de utentes que se dirigiram à consulta de clínica geral, nos CS seleccionados. Resultados: Incluíramse 1.201 utente...
Hepatite C em toxicodependentes: acompanhamento e acesso à terapêutica
Castro, R; Valente, C; Ramos, J; Almeida, J; Marinho, R; Branco, T; Andrade, S; Macedo, AA hepatite C constitui, actualmente, um grave problema de saúde pública. Estima-se que existam, em todo o mundo, 180 milhões de pessoas com infecção crónica por vírus da hepatite C (VHC) e que a sua prevalência na população portuguesa varie entre 1 e 1,5%. Em Portugal, não existem normas de orientação actualizadas de tratamento, nem recomendações para o diagnóstico e acompanhamento dos doentes com VHC e, em par...
Aeroallergens sensitization in an allergic paediatric population of Cova da Bei...
Loureiro, G; Rabaça, MA; Blanco, B; Andrade, S; Chieira, C; Pereira, CCova da Beira is an interior central region of Portugal, with a population of 93,000 inhabitants. The first pollen counts performed in Portugal revealed the highest values of the country in this area. The aim of this study was to assess the aeroallergens sensitization in an allergic population, according to the age groups. In a 5 year period (1995-2000) 1790 consecutive outpatients were observed for suspected a...
Ferritin in patients under dialysis.
Silva, F J; Andrade, S; Aguilar, L; Ribeiro, O; Salgadinho, M A; Simões, J