Introduction: Gastric cancer (GC), as a multifactorial disease, exhibits a complex pathogenesis, having intra- and inter-tumor heterogeneity, challenging the efficacy of current treatments[1,2]. GC as a major global health problem, better diagnostic and therapeutic strategies are needed, leading to further biomarkers research associated to innovative targeted therapies[3,4]. Objectives: Our aim was to study hum...
The present contribution updates BORGES et al. (2008)’s “A list of the terrestrial fungi, flora and fauna of Madeira and Selvagens archipelagos”. Since then, and until the summer of 2019, 131 new taxa were cited, namely 30 bryophytes, one pteridophyte and 100 spermatophytes. Based on the compilation of written and unpublished information about the diversity of terrestrial plants cited for Porto Santo, the prese...
Vascular complications contribute significantly to the extensive morbidity and mortality rates observed in people with diabetes. Despite well known that the diabetic kidney and heart exhibit imbalanced angiogenesis, the mechanisms implicated in this angiogenic paradox remain unknown. In this study, we examined the angiogenic and metabolic gene expression profile (GEP) of endothelial cells (ECs) isolated from a ...
Introdução: O aleitamento materno está universalmente reconhecido como o método preferencial de alimentação do bebé, especialmente nos primeiros 6 meses de vida. No entanto, para muitas mulheres, as dificuldades no aleitamento materno resultam na sua cessação precoce. A dor mamária e a dor mamilar são queixas comuns da lactante e dos motivos mais frequentes de interrupção da amamentação. A mastite a Candida é u...
Introduction: Female sexual dysfunction is a common problem, affecting more than 1/3 of women during their lives. The aim of this review is to review the evidence for the effectiveness of testosterone in sexual dysfunction in postmenopausal women, particularly in the improvement of sexual desire.Material and Methods: The authors searched in international databases National Guidelines Clearinghouse, Guidelines F...
This study aimed to evaluate the effect of milk fermented with Lactobacillus acidophilus 145 and Bifidobacterium longum BB536 on plasma lipids in a sample of adult women. A double-blind, placebo controlled, cross-over study (two periods of four weeks each separated by a 1-week washout period) was performed in 34 women, aged between 18 and 65 years. Group A consumed 125 g fermented milk three times a day for the...