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Synthesis and Evaluation of Cytotoxic Effects of Amino-ester Derivatives of Nat...
Victor,Mauricio M.; David,Jorge M.; Santos,Marcelo A. S. dos; Barreiros,André L. B. S.; Barreiros,Marizeth L.; Andrade,Fernanda S.; Carvalho,Adriana A.Natural α,β-amyrins were isolated from endemic Brazilian Esenbeckia grandiflora Mart., and eight synthetic derivatives were obtained by esterification reactions with bromo acetate, followed by amine treatment. The structures of the all compounds were confirmed by 1H and 13C nuclear magnetic resonance (NMR), Fourier transform infrared (FTIR) and high-resolution mass spectrometry (HRMS) data analysis. The derivat...
Date: 2017
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Origin: Oasisbr