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Effects of propofol in lipid-based emulsion and in microemulsion on the inciden...

Paço,Cristian Durço; Vane,Matheus Fachini; Andrade,Rafael Bicarato de; Domingues,Maria Aparecida; Carvalho,Lidia Raquel de; Santos,Daniela Carvalho dos

PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME). METHODS: Forty-two rabbits (2.5-4.5 Kg) were randomly allocated into seven groups of six animals each: SHAM- surgical treatment alone; Bolus Control Group - 3 mL-intravenous (IV) bolus of saline; Continuous Infusion Control Group - 3 mL- I...

Date: 2013   |   Origin: Oasisbr

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