2 documents found, page 1 of 1
Retinal OCT speckle as a biomarker for glaucoma diagnosis and staging
Vaz, Pedro G.; Brea, Luisa Sanchez; Silva, Vânia Bastos; van Eijgen, Jan; Stalmans, Ingeborg; Cardoso, João; van Walsum, Theo; Klein, StefanThis paper presents a novel image analysis strategy that increases the potential of macular Optical Coherence Tomography (OCT) by using speckle features as biomarkers in different stages of glaucoma. A large pool of features (480) were computed for a subset of macular OCT volumes of the Leuven eye study cohort. The dataset contained 258 subjects that were divided into four groups based on their glaucoma severit...
Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomark...
Paulo, Alice; Vaz, Pedro G.; Andrade De Jesus, Danilo; Sánchez Brea, Luisa; Van Eijgen, Jan; Cardoso, João; van Walsum, Theo; Klein, StefanThe lamina cribrosa (LC) is an active structure that responds to the strain by changing its morphology. Abnormal changes in LC morphology are usually associated with, and indicative of, certain pathologies such as glaucoma, intraocular hypertension, and myopia. Recent developments in optical coherence tomography (OCT) have enabled detailed in vivo studies about the architectural characteristics of the LC. Struc...