IntroductionEssential oils (EO), rich in bioactive metabolites with biocidal activity, present great potential for agricultural applications as new biopesticides. However, their high volatility and sensitivity to environmental conditions limits their application. To address these limitations, nanotechnology-based formulations have been developed, incorporating EO into natural clays such as montmorillonite (MMT)...
Background & Aim: The dependency on crops of products with chemical compounds, whether fertilizers or pesticides, for saving the development and yield has been a challenge to the environment, and new alternatives are being sought to change this reality. The excessive use of chemicals affects human health and soil quality. There is a significant need to produce green compounds that are environmentally sustainabl...
Introduction: The dependency on crops of products with synthetic chemical compounds, whether fertilizers or pesticides, for saving the development and yield has been a challenge to the environment, and new alternatives are being sought to change this reality. The excessive use of chemicals affects human health and soil quality. Therefore, there is a significant need to produce green compounds that are environme...
A procura intensa por novas fontes de energia mais sustentáveis, como a produção de hidrogénio através do processo de separação dos componentes da molécula água, tem estado associada à implementação de estratégias e políticas promotoras da neutralidade carbónica das sociedades. Neste sentido, têm sido realizados esforços para explorar catalisadores, para o processo de hidrólise da água, baseados em compostos me...
Scientific research in the field of veterinary pharmacology has provided new opportunities for the development of modified release dosage forms, with the aim to improve therapeutic efficacy and reduce animal stress. The formulation of classical drug molecules with advanced biomaterials has become a new approach to increasing drug bioavailability and improving the therapeutic outcome. The main reasons for the de...
Apesar dos benefícios e da necessidade para o sector agroalimentar no controlo de diversas pragas e doenças, a utilização excessiva e generalizada de inseticidas convencionais pode ocasionar contaminação ambiental em vários níveis. Nos últimos anos, a aplicação da nanotecnologia tem beneficiado o setor agroalimentar no controlo mais sustentável de pragas, por proporcionar o desenvolvimento de nanopesticidas, em...
Made available in DSpace on 2022-04-28T19:02:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-10-01; In the recent decades, numerous drug delivery systems based on nanoparticles have been developed. To deliver drugs to a specific site, many vehicles have been designed, including liposomes, lipid and polymeric nanoparticles. However these systems can suffer some limitations such as thermal and physical ...
Several therapeutic properties have been attributed to epigallocatechin gallate (EGCG), a phytopharmaceutical polyphenol with antioxidant and antiproliferative activity. EGCG is however very prone to oxidation in aqueous solutions which changes its bioactive properties. Its loading in nanoparticles has been proposed to reduce its degradation while increasing its in vivo efficacy. The aim of this study was to co...
The present work reports the effect of polysaccharides (chitosan and sodium alginate) on silica nanoparticles (SiNP) for hydrophilic molecules delivery taking insulin as model drug. The influence of tetraethyl orthosilicate (TEOS) and homogenization speed on SiNP properties was assessed by a 22 factorial design achieving as optimal parameters: 0.43 mol/L of TEOS and homogenization speed of 5000 rpm. SiNP mean p...
Made available in DSpace on 2019-10-06T15:51:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-07-01; Fundação para a Ciência e a Tecnologia; The present work reports the effect of polysaccharides (chitosan and sodium alginate) on silica nanoparticles (SiNP) for hydrophilic molecules delivery taking insulin as model drug. The influence of tetraethyl orthosilicate (TEOS) and homogenization speed on SiNP ...