3 documents found, page 1 of 1
Body composition and respiratory outcomes in children: a population-based prosp...
Wu, T; Santos, S; Quezada-Pinedo, HG; Vernooij, MW; Jaddoe, VWV; Klein, S; Duijts, L; Oei, EHGBackgroundBody composition might influence lung function and asthma in children, but its longitudinal relations are unclear. We aimed to identify critical periods for body composition changes during childhood and adolescence in relation to respiratory outcomes in adolescents.MethodsIn a population-based prospective cohort study, we measured body mass index, fat mass index (FMI), lean mass index (LMI) and the ra...
Short term associations of ambient nitrogen dioxide with daily total, cardiovas...
Meng, X; Liu, C; Chen, R; Sera, F; Vicedo-Cabrera, AM; Milojevic, A; Guo, Y; Tong, S; Coelho, MSZS; Saldiva, PHN; Lavigne, E; Correa, PM; Ortega, NVObjective To evaluate the short term associations between nitrogen dioxide (NO2) and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide, using a uniform analytical protocol. Design Two stage, time series approach, with overdispersed generalised linear models and multilevel meta-analysis. Setting 398 cities in 22 low to high income countries/regions. Main outcome measure...
Gene Silencing via PDA/ERK2-siRNA-Mediated Electrospun Fibers for Peritendinous...
Liu, S; Wu, F; Gu, S; Wu, T; Chen, S; Chen, S; Wang, C; Huang, G; Jin, T; Cui, W; Sarmento, B; Deng, L; Fan, CSustained delivery of small interfering RNA (siRNA) is a challenge in gene silencing for managing gene-related disorders. Although nanoparticle-mediated electrospun fibers enable sustainable gene silencing, low efficiency, loss of biological activity, toxicity issues, and complex electrospinning techniques are all bottlenecks of these systems. Preventing peritendinous adhesion is crucial for their successful us...