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Choosing sheep (Ovis aries) as animal model for temporomandibular joint researc...

Angelo, D.F.; Morouço, P.; Alves, N.; Viana, T.; Santos, F.; González, R.; Monje, F.; Macias, D.; Carrapiço, B.; Sousa, R.; Cavaco-Gonçalves, S.

Preclinical trials are essential to the development of scientific technologies. Remarkable molecular and cellular research has been done using small animal models. However, significant differences exist regarding the articular behavior between these models and humans. Thus, large animal models may be more appropriate to perform trials involving the temporomandibular joint (TMJ). The aim of this work was to make...

Date: 2016   |   Origin: IC-online

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