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Influence of passage number on the impact of the secretome of adipose tissue st...

Serra, Sofia Cravino; Costa, João C.; Silva, Rita Catarina Assunção Ribeiro; Teixeira, Fábio Gabriel Rodrigues; Silva, Nuno André Martins

Mesenchymal stem cells (MSCs), and within them adipose tissue derived stem cells (ASCs), have been shown to have therapeutic effects on central nervous system (CNS) cell populations. Such effects have been mostly attributed to soluble factors, as well as vesicles, present in their secretome. Yet, little is known about the impact that MSC passaging might have in the secretion therapeutic profile. Our aim was to ...

Date: 2018   |   Origin: RepositóriUM - Universidade do Minho
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