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Next-Generation Allergic Rhinitis and Its Impact on Asthma (ARIA) Guidelines fo...
Bousquet, J; Schünemann, HJ; Togias, A; Bachert, C; Erhola, M; Hellings, PW; Klimek, L; Pfaar, O; Wallace, D; Ansotegui, I; Agache, I; Walker, SThe selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlle...
Off-label prescribing for allergic diseases in children
Silva, D; Ansotegui, I; Morais-Almeida, MThe majority of drugs prescribed have not been tested in children and safety and efficacy of children's medicines are frequently supported by low quality of evidence. Therefore, a large percentage of prescriptions for children in the clinical daily practice are used off label. Despite the several recent legislation and regulatory efforts performed worldwide, they have not been successful in increasing availabil...