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In vivo activity of peptide-ionic liquid conjugates against diabetic wounds

Gomes, A.; Ferraz, Ricardo; Ferreira, M.; Maciel, J.; Plácido, A.; Leal, E.; Gameiro, P.; Gonçalves, Teresa; Carvalho, E.; Gomes, P.

Due to widespread multidrug-resistant (MDR) microbes, efficient treatments for infected wounds are being exhausted, which means that there is an alarming lack of effective antibiotics to treat diabetic foot ulcers (DFU). The increasing life expectancy of the population and the growing incidence of unhealthy lifestyles is leading to a concerning rise in the number of people affected with diabetes and related com...


Bisphenol A migration from plastic materials: direct insight of ecotoxicity in ...

Mansilha, Catarina; Silva, Poliana; Rocha, Sónia; Gameiro, P.; Domingues, Valentina F.; Pinho, Carina; Ferreira, Isabel M. P. L. V. O.

Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) whose migration from food packaging is recognized worldwide. However, the real overall food contamination and related consequences are yet largely unknown. Among humans, children’s exposure to BPA has been emphasized because of the immaturity of their biological systems. The main aim of this study was to assess the reproductive impact of BPA leached fr...


Occurrence of bisphenol A, estrone, 17b-estradiol and 17a-ethinylestradiol in P...

Rocha, Sónia; Domingues, Valentina F.; Pinho, Carina; Fernandes, Virgínia C.; Delerue-Matos, Cristina; Gameiro, P.; Mansilha, Catarina

This study focused on the occurrence of several EDCs including bisphenol A, estrone (E1), the 17b-estradiol (E2) and 17a- thinylestradiol (EE2) in fourteen rivers of Portugal. Samples analysis revealed a widespread contamination of BPA especially in Ave, Cávado, Douro, Ferro, Sousa and Vizela Rivers. Achieving 98.4 ng/L for the highest concentration. The estrogens achieved above the method quantification limit ...


Interlaboratory validation of an environmental monitoring method for trace anal...

Mansilha, Catarina; Rocha, Sónia; Gameiro, P.; Pinho, Carina; Ferreira, Isabel M. P. L. V. O.; Silva, Poliana; Domingues, Valentina F.

Environmental pollution continues to be an emerging study field, as there are thousands of anthropogenic compounds mixed in the environment whose possible mechanisms of toxicity and physiological outcomes are of great concern. Developing methods to access and prioritize the screening of these compounds at trace levels in order to support regulatory efforts is, therefore, very important. A methodology based on s...


Groundwater from infiltration galleries used for small public water supply syst...

Mansilha, Catarina; Melo, A.; Ferreira, Isabel M. P. L. V. O.; Pinho, O.; Domingues, Valentina F.; Pinho, C.; Gameiro, P.

Infiltration galleries are among the oldest known means used for small public water fountains. Owing to its ancestral origin they are usually associated with high quality water. Thirty-one compounds, including pesticides and estrogens from different chemical families, were analysed in waters from infiltration galleries collected in Alto Douro Demarcated Wine region (North of Portugal). A total of twelve compoun...


Emerging water contaminants

Mansilha, C.; Melo, A.; Ferreira, I.; Domingues, V.; Pinho, C.; Rocha, S.; Gameiro, P.


Bisphenol a releasing by plastic container with gas chromatography tandem mass ...

Rocha, S.; Domingues, V.F.; Mansilha, C.; Pinho, C.; Gameiro, P.; Delerue-Matos, C.


Groundwater from infiltration galleries used for small public water supply syst...

Mansilha, C.; Melo, A.; Ferreira, I.; Pinho, O.; Domingues, V.; Pinho, C.; Gameiro, P.

Infiltration galleries are among the oldest known means used for small public water fountains. Owing to its ancestral origin they are usually associated with high quality water. Thirty-one compounds, including pesticides and estrogens from different chemical families, were analysed in waters from infiltration galleries collected in Alto Douro Demarcated Wine region (North of Portugal). A total of twelve compoun...


Evaluation of the actual standard procedures for analysis of total extractable ...

Pinho, C.; Mansilha, C.; Gameiro, P.

Hundreds of different hydrocarbon compounds derived from agricultural, industrial and domestic practices are released daily into aquatic systems with adverse effects in the desirable potable characteristics, in aquatic fauna and flora, and on tourism, recreation and aesthetics of the impacted areas. Total petroleum hydrocarbon concentration data cannot be used to quantitatively estimate human health risk, but c...


Groundwater from Infiltration Galleries Used for Small Public Water Supply Syst...

Mansilha, Catarina; Melo, A.; Ferreira, Isabel; Pinho, Olívia; Domingues, V.; Pinho, C.; Gameiro, P.

Infiltration galleries are among the oldest known means used for small public water fountains. Owing to its ancestral origin they are usually associated with high quality water. Thirty-one compounds, including pesticides and estrogens from different chemical families, were analysed in waters from infiltration galleries collected in Alto Douro Demarcated Wine region (North of Portugal). A total of twelve compoun...


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