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Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: E...

Taheri, Y; Sharifi-Rad, J; Antika, G; Yilmaz, YB; Tumer, TB; Abuhamdah, S; Chandra, S; Saklani, S; Kiliç, CS; Sestito, S; Dastan, SD; Kumar, M

Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing to their biological and pharmacological value. Many preclinical studies report that luteolin present excellent antioxidant, anticancer, antimicrobial, neuroprotective, cardioprotective, a...


Bioactive Compounds as Potential Agents for Sexually Transmitted Diseases Manag...

Sharifi-Rad, J; Quispe, C; Rahavian, A; Pereira Carneiro, JN; Rocha, JE; Alves Borges Leal, AL; Bezerra Morais Braga, MF; Melo Coutinho, HD

Sexually transmitted diseases (STDs) are produced by pathogens like bacteria, fungi, parasites, and viruses, and may generate severe health problems such as cancer, ulcers, and even problems in the newborn. This narrative review aims to present updated information about the use of natural bioactive compounds for the prevention and treatment of sexually transmitted infections. A search of the literature was perf...


Insights on the use of a-lipoic acid for therapeutic purposes

Salehi, B; Yilmaz, YB; Antika, G; Boyunegmez, TT; Fawzi, MM; Lobine, D; Akram, M; Riaz, M; Capanoglu, E; Sharopov, F; Martins, N; Cho, WC

a-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where it is used as a cofactor for pyruvate dehydrogenase (PDH) and a-ketoglutarate dehydrogenase co...


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