24 documents found, page 1 of 3
A systematic practice review: providing palliative care for people with Parkins...
Garon, Michela; Weck, Christiane; Rosqvist, Kristina; Odin, Per; Schrag, Anette; Krikmann, Ülle; Pedrosa, David J; Antonini, Angelo; Lorenzo, StefanBackground: People with Parkinson’s disease has significant and increasing physical, psychosocial and spiritual needs, as well as problems with coordination and continuity of care. Despite the benefits that palliative care could offer, there is no consensus on how it should be delivered. Aim: The aim of this study is to provide a pragmatic overview of the evidence to make clinical recommendations to improve pal...
Confusion of evidence‐based reviews and guidelines
Deuschl, Günther; Antonini, Angelo; Costa, João; Śmiłowska, Katarzyna; Berg, Daniela; Corvol, Jean‐Christophe; Fabbrini, Giovanni; Ferreira, Joaquim JHariz and colleagues [1] argue that the new EAN/MDS GL contradicts the repeated endorsements of pallidotomy by the MDS. The MDS has previously published “evidence based medicine (EBM) reviews,” which appraise each treatment on the basis of welldefined criteria but are not GLs. Clinical GLs, such as the new EAN/MDS GL, also take into consideration other variables, including context, summarizing the current medic...
Optimizing levodopa therapy, when and how? Perspectives on the importance of de...
Lees, Andrew; Tolosa, Eduardo; Stocchi, Fabrizio; Ferreira, Joaquim J; Rascol, Olivier; Antonini, Angelo; Poewe, WernerIntroduction: There is currently a resurgence of levodopa as the initial treatment of choice for most patients with Parkinson's disease, albeit at lower doses than previously used. The addition of adjuvant treatments (including MAO-B inhibitors, COMT inhibitors and dopamine agonists) is an established strategy to reduce motor complications that develop with sustained levodopa therapy. Areas covered: In this nar...
Defining the riddle in order to solve it: there is more than one “Parkinson's d...
Outeiro, Tiago; Alcalay, Roy N.; Antonini, Angelo; Attems, Johannes; Bonifati, Vincenzo; Cardoso, Francisco; Chesselet, Marie‐Françoise; Hardy, JohnBackground: More than 200 years after James Parkinsondescribed a clinical syndrome based on his astute observations, Parkinson's disease (PD) has evolved into a complex entity, akin to the heterogeneity of other complex human syndromes of the central nervous system such as dementia, motor neuron disease, multiple sclerosis, and epilepsy. Clinicians, pathologists, and basic science researchers evolved arrange of...
Does the 5–2-1 criteria identify patients with advanced Parkinson's disease? Re...
Malaty, Irene A.; Martinez-Martin, Pablo; Chaudhuri, K. Ray; Odin, Per; Skorvanek, Matej; Jimenez-Shahed, Joohi; Soileau, Michael J.; Lindvall, SusannaBackground: The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinson’s disease (APD) and suboptimal medication control. The 5–2-1 criteria was proposed by clinical consensus to identify patients with advancing PD. Our objective was to evalua...
Psychometric properties of clinical indicators for identification and managemen...
Antonini, Angelo; Pahwa, Rajesh; Odin, Per; Henriksen, Tove; Soileau, Michael J.; Rodriguez-Cruz, Ramon; Isaacson, Stuart H.; Merola, AristideIntroduction: Standardized and validated criteria to define advanced Parkinson’s disease (PD) or identify patient eligibility for device-aided therapy are needed. This study assessed the psychometric properties of clinical indicators of advanced PD and eligibility for device-aided therapy in a large population. Methods: This retrospective analysis of the Adelphi Parkinson’s Disease Specific Programme collected ...
Moving towards integrated and personalized care in Parkinson's disease: a frame...
van Munster, Marlena; Stümpel, Johanne; Thieken, Franziska; Pedrosa, David; Antonini, Angelo; Côté, Diane; Fabbri, Margherita; Ferreira, Joaquim JDelivering healthcare to people living with Parkinson's disease (PD) may be challenging in face of differentiated care needs during a PD journey and a growing complexity. In this regard, integrative care models may foster flexible solutions on patients' care needs whereas Parkinson Nurses (PN) may be pivotal facilitators. However, at present hardly any training opportunities tailored to the care priorities of P...
Access and attitudes toward palliative care among movement disorders clinicians
Miyasaki, Janis M.; Lim, Shen‐Yang; Chaudhuri, K. Ray; Antonini, Angelo; Piemonte, Maria; Richfield, Edward; Alburquerque Gonzalez, DanielaBackground: Neuropalliative care is an emerging field for those with neurodegenerative illnesses, but access to neuropalliative care remains limited. Objective: We sought to determine Movement Disorder Society (MDS) members' attitudes and access to palliative care. Methods: A quantitative and qualitative survey instrument was developed by the MDS Palliative Care Task Force and e-mailed to all members for comple...
The impact of COVID-19 on palliative care for people with Parkinson’s and respo...
Chaudhuri, K Ray; Rukavina, Katarina; McConvey, Victor; Antonini, Angelo; Lorenzl, Stefan; Bhidayasiri, Roongroj; Piemonte, Maria Elisa PimentelIntroduction: Although in some countries, palliative care (PC) still remains poorly implemented, its importance throughout the course of Parkinson's disease (PD) is increasingly being acknowledged. With an emergence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic, growing emphasis has been placed on the palliative needs of people with Parkinson's (PwP), particularly elderly, frail, and ...
Moving towards home-based community-centred integrated care in Parkinson's disease
Fabbri, Margherita; Caldas, Ana Castro; Ramos, Joana B.; Sanchez-Ferro, Álvaro; Antonini, Angelo; Růžička, Evžen; Lynch, Timothy; Rascol, OliverPeople living with Parkinson's disease (PwP) experience a wide range of motor and non-motor symptoms associated with increasing complexity of care delivery. A multispecialty approach has been presented as an intuitive solution for tailored and comprehensive care delivery. Nevertheless, past trials of both multidisciplinary or interdisciplinary care models in PD suggested no measurable change to a small benefit ...