3 documents found, page 1 of 1
A case of severe Covid-19 infection as the first manifestation of Cushing’s dis...
Guia Lopes, Maria Leonor; Cidade, José Pedro; Antunes, Carolina; Limbert, Clotilde; Duarte, João SequeiraPublisher Copyright: © 2024 the author(s).; Cushing's disease (CD) is characterized by distinct syndromic features, often accompanied by obesity and depression. However, considering its gradual onset of symptoms, it is usually associated with diagnostic delays. In rare instances, CD may lead to severe infections due to the observed immunosuppression in affected individuals. We present a rare case of an undiagno...
Drug repurposing for identification of new efflux inhibitors and/or antibiofilm...
Neves, Joana; Antunes, Carolina; Andrade, Mariana; Couto, Isabel; Rodrigues, Liliana; Costa, Sofia SantosBackground Staphylococcus aureus (SA) and Staphylococcus epidermidis (SE) are frequent pathogens causing nosocomial infections. Efflux-mediated resistance and biofilm formation may contribute to the emergence of resistance in these species and resilience of such infections to chemotherapeutics. In this work, we applied an in silico drug repurposing strategy to identify drugs that can target efflux and/or biofil...
Drug repurposing for identification of new efflux inhibitors and/or antibiofilm...
Neves, Joana; Antunes, Carolina; Andrade, Mariana; Bento, Maria; Couto, Isabel; Rodrigues, Liliana; Costa, Sofia Santos