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Comparative analysis of the phytochemical profiles in the flowers and pods of A...

Pedro, Soraia; Fernandes, Tiago A.; Antunes, Alexandra M.M.; Gonçalves, José Carlos; Gominho, Jorge; Gallardo, Eugenia; Anjos, O.

As espécies do género Acacia são plantas invasoras e extremamente agressivas em vários territórios, representando uma ameaça significativa à biodiversidade e ao equilíbrio dos ecossistemas. Alguns estudos têm sido realizados sobre a composição e atividade biológica em diferentes partes da árvore. Este trabalho tem como objetivo caracterizar extratos de Acacia mearnsii para potencial aplicação industrial.


First chemical profile analysis of acacia pods

Pedro, Soraia; Fernandes, Tiago A.; Luís, Ângelo; Antunes, Alexandra M.M.; Gonçalves, José Carlos; Gominho, Jorge; Gallardo, Eugenia; Anjos, O.

This study intended to evaluate the potential industrial applications of various Acacia species (Acacia melanoxylon, Acacia longifolia, Acacia cyclops, Acacia retinodes, Acacia pycnantha, Acacia mearnsii, and Acacia dealbata) by examining their chemical composition, antioxidant, and antimicrobial properties. Using high-resolution mass spectrometry, a comprehensive analysis successfully identified targeted compo...


Metabolic stability and metabolite profiling of emerging synthetic cathinones

Lopes, Rita P.; Ferro, Raquel A.; Milhazes, Margarida; Figueira, Margarida; Caldeira, Maria João; Antunes, Alexandra M.M.; Gaspar, Helena

Synthetic cathinones constitute the second largest groups of new psychoactive substances (NPS), which are especially popular among adolescents and young adults. Due to their potential toxicity, the recreational use of these NPS constitute a serious worldwide public health problem. However, their fast appearance in the market renders the continuous updating of NPS information highly challenging for forensic auth...

Date: 2023   |   Origin: IC-online

Identification of gallotannins and ellagitannins in aged wine spirits : a new p...

Fernandes, Tiago A.; Antunes, Alexandra M.M.; Caldeira, Ilda; Anjos, O.; Freitas, Victor; Fargeton, Laurent; Boissier, Benjamin; Catarino, Sofia

This research was focused on identifying gallotannins and ellagitannins degradation pathways to better understand their behavior in complex media such as wine spirits (WS). A WS was aged with chestnut wood staves with three levels of micro-oxygenation, nitrogen, and using wooden barrels. Gallotannins and ellagitannins were identified by LC-ESI-HRMS/MS using a Q-TOF in samples collected at 8, 21, 60, 180, 270, a...


Casting light on the chemical characterization of acacia pods

Pedro, Soraia; Fernandes, Tiago A.; Antunes, Alexandra M.M.; Gominho, Jorge; Gallardo, Eugenia; Anjos, O.

Invasive species impose a strain on natural ecosystems by contributing to the loss of certain native species. Acacia species are amongst the most aggressive invasive species in Portugal. In this work, Acacia retinodes, A. longifolia, A. melanoxylon, A. pycnantha and A. dealbata pods were studied concerning the extraction of compounds for potential industrial application.


Hydrolysable tannins in aged wine spirits: a fresh perspective using alternativ...

Fernandes, Tiago A.; Antunes, Alexandra M.M.; Alves, Sheila Oliveira; Caldeira, Ilda; Anjos, O.; Catarino, Sofia; Canas, Sara

Wine spirits (WSs) are usually aged in wooden barrels, but using wood pieces instead of barrels, with or without micro-oxygenation, is a technological alternative that has been investigated by our team.


Identification of gallotannins and ellagitannins in aged wine spirits: A new pe...

Fernandes, Tiago A.; Antunes, Alexandra M.M.; Caldeira, Ilda; Anjos, Ofélia; Freitas, Victor; Fargeton, Laurent; Boissier, Benjamin; Catarino, Sofia

This research was focused on identifying gallotannins and ellagitannins degradation pathways to better understand their behavior in complex media such as wine spirits (WS). A WS was aged with chestnut wood staves with three levels of micro-oxygenation, nitrogen, and using wooden barrels. Gallotannins and ellagitannins were identified by LC-ESI-HRMS/MS using a Q-TOF in samples collected at 8, 21, 60, 180, 270, a...


Integration of cellular and molecular endpoints to assess the toxicity of polyc...

Morgado, Patrícia I.; Jose, Sílvia; Wanke, Riccardo; Antunes, Alexandra M.M.; Sofia Cardoso, Ana; Jordao, Luisa

Polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants present in the environment with known mutagenic and carcinogenic properties. In the present study the effect of exposure to single or multiple doses of benzo[a]anthracene (BaA), pyrene (Pyr) and three halogenated derivatives of these compounds (1-ClPyr; 1-BrPyr and 7-ClBaA) were evaluated in a liver-derived human cell line (HepG2). Cytotoxicity a...


Chlorinated Polycyclic Aromatic Hydrocarbons Associated with Drinking Water Dis...

Pinto, Miguel; Rebola, Marlene; Louro, Henriqueta; Antunes, Alexandra M.M.; José, Silvia S.; Rocha, Maria; Silva, Maria João; Cardoso, Ana Sofia

Polycyclic aromatic hydrocarbons (PAHs) are among the most persistent and toxic organic micropollutants present in water and several of them are mutagenic and carcinogenic. Although it has been shown that chlorinated derivatives of PAHs (Cl-PAHs) may be formed during the water chlorination procedure, little is known about their potential genotoxic and carcinogenic effects. The objectives of the present work wer...


Formação de subprodutos de desinfeção da água e avaliação do seu potencial geno...

Pinto, Miguel; Rebola, Marlene; Louro, Henriqueta; Antunes, Alexandra M.M.; José, Sílvia S.; Rocha, M. Raquel; Silva, M. João; Cardoso, Ana Sofia


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