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Pearls & oy-sters: a challenging optic neuropathy: what not to miss in optic ne...
Vidal, Maria Isabel; Antunes, Ana Patrícia; Morgado, Carlos; Simas, Nuno; Roque, Rafael; Albuquerque, LuísaOptic neuropathies include a wide range of disorders from ischemic, toxic, demyelinating, or inflammatory processes with acute/subacute onset to more gradual compressive or genetic etiologies. Accurate clinical history and multimodality optic nerve imaging including MRI and optical coherence tomography have greatly improved the diagnosis of patients with optic neuropathies. We report a case of a woman with seve...
Combined central and peripheral demyelination after COVID-19 vaccination
Coelho, Pedro; Paula, André; Martins, Isabel Vidal; Falcão De Campos, Catarina; Ferreira, João; Antunes, Ana Patrícia; Albuquerque, LuísaCombined central and peripheral demyelination (CCPD) is a rare neurological entity that afects both the central and peripheral nervous system with demyelinating lesions. The pattern of involvement of the central nervous system (CNS) includes frequent bilateral optical neuritis, involvement of grey matter and occasional longitudinally extensive transverse myelitis (LETM) in the absence of oligoclonal bands (OCB)...
Occipital lobe seizures as presentation of an hyperglycemic state: a case report
Rodrigues, Catarina; Santos Silva, Cláudia; Coelho, Pedro; Antunes, Ana Patrícia; Falcão, Filipa; Albuquerque, LuísaSeveral neurological manifestations may be associated with hyperosmotic hyperglycemic nonketotic state (HHNK). Forty percent of HHNK patients have acute symptomatic seizures, mostly focal. Motor seizures, such as epilepsia partialis continua, are the most common, while non motor ones are less recognized. Epileptic disorders of visual perception are rarely reported. We report a case of inaugural diabetes, involv...
Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte g...
Dias Da Costa, Mariana; Leal Rato, Miguel; Cruz, Diana; Valadas, Anabela; Antunes, Ana Patrícia; Albuquerque, LuísaWe report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid ther...
Consensus Protocol for the Treatment of Super-Refractory Status Epilepticus
Gomes, Daniel; Pimentel, José; Bentes, Carla; Aguiar de Sousa, Diana; Antunes, Ana Patrícia; Alvarez, António; Silva, Zélia Costa eIntroduction: Super-refractory status epilepticus is defined as status epilepticus that persists or recurs 24 hours after anaesthetic therapy onset or after its withdrawal. It is mostly found in intensive care units and carries high mortality but good long-term prognosis for those who survive. In contrast with the initial phases of status epilepticus, treatment lacks strong scientific evidence and is mostly der...