39 documents found, page 1 of 4

In vitro permeability of MDPV across Caco-2 cells for assessment of intestinal ...

Background: Synthetic cathinones, such as 3,4-methylenedioxypyrovalerone (MDPV), are widely studied chiral psychoactive substances [1]. Enantioselectivity studies on the toxicokinetic of synthetic cathinones are still scarce [2], namely on their ability to cross the intestinal membrane, which was evaluated only for methylone and pentedrone [3]. To isolate enantiomers for these studies, liquid chromatography (LC...

Antifungal activity of a new derivative of 5-aminoimidazole-4-carbohydrazonamide

[Excerpt] Fungal infections, as recognized by the World Health Organization (WHO), are among the most worrying challenges for the medical community due to their high incidence, recurrence, and the emergence of resistance to the few available drugs and therapies. The discovery of new molecules with antifungal activity, exhibiting new mechanisms of action and less side effects, thus represents an important step f...

Respiração na técnica kokyo de karaté em imagética estática e em execução motor...

No karaté o movimento está em estreita articulação com um fluxo respiratório diafragmático controlado. Como a respiração diafragmática ativa o sistema nervoso parassimpático e reduz a frequência respiratória (CR), fomos verificar se crianças e jovens de diferentes graduações de karaté revelavam alteração na CR e na variabilidade da frequência cardíaca (VFC), nas condições de imagética estática (I) e de execução...

Lipid metabolism in iron overloaded mice adipose tissue

The subcutaneous adipose tissue from HFE-knockout mice accumulates high levels ...

Tento seed germination and seedling emergence (Ormosia paraensis Ducke – Fabaceae)

Made available in DSpace on 2022-04-28T19:10:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-30; Ormosia paraensis Ducke, known as “tento”, has seeds used to make handicrafts and wood worked by furniture makers. Despite its importance in handcrafted, timber and for the recovery of degraded areas, there is little research on the physiology of its seeds in order to help the production of seedlings in...

Community-based savings groups: An alternative model for resilience

This study explores the potential of internal and contextual factors that contribute to the formation of village savings and loan associations and provides a testimonial of individuals that benefit from those groups in northern Mozambique, part of the community-based savings groups (CBSG). The CBSG is the improved mechanism of that community initiative aiming to facilitate the expansion of these groups; promote...

Sensing the impact of COVID-19 restrictions from online reviews: The cases of L...

This study aims to understand how the COVID-19 pandemic affected the hotel sector and to identify the current traveler demands. The traveler’s re-views were analyzed based on sentiment analysis and a guest satisfaction model was also proposed, demonstrating a data mining approach within tourism and hospitality research. Given its popularity, TripAdvisor was the chosen platform for collection of hotel reviews in...

Systematic review on the applicability of principal analysis components for the...

The principal component analysis (PCA) is a dimensionality reduction method that has identified significant differences in older adults' motion analysis, previously not detected by discrete exploration of biomechanical variables. This systematic review aims to synthesize the current evidence regarding PCA use in the study of movement in older adults (kinematics and kinetics), summarizing the tasks and biomechan...

Non-invasive monitoring with ballistocardiographic sensors for sleep management

Sleep has an important impact on people's daily lives. A successful methodology for monitoring sleep is Polysomnography (PSG). This is an accurate and reliable approach but, unfortunately, very invasive. PSG uses expensive sensors that must be positioned by experts, what, in practice, makes its adoption only viable in hospital setups. Therefore, there is a demand for better non-invasive alternatives, such as Ba...