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Alleles of HLA-DRB1∗04 associated with pulmonary tuberculosis in Amazon Brazili...
Lima, Dhêmerson Souza de; Ogusku, Maurício Morishi; Santos, Maria Cristina dos; Silva, Cláudia Maria de Melo; Almeida, Vanessa Alves deImmunogenetic host factors are associated with susceptibility or protection to tuberculosis (TB). Strong associations of HLA class II genes with TB are reported. We analyzed the HLA-DRB1∗04 alleles to identify subtypes associated with pulmonary TB and their interaction with risk factors such as alcohol, smoking, and gender in 316 pulmonary TB patients and 306 healthy individuals from the Brazilian Amazon. The H...
Data: 2020
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Origem: Oasisbr