Surgically resected epidermal growth factor receptor-mutated non-small cell lung cancer continues to carry a substantial risk of recurrence. The aim of this retrospective, single-center study, conducted at a Portuguese tertiary hospital was to evaluate the clinical course of these patients, diagnosed between 2016 and 2020, with the final clinical data review in November, 2024. A total of 48 patients were includ...
As hemoglobinopatias estão entre as doenças genéticas mais frequentes no mundo e podem representar um desafio ao diagnóstico devido à sua elevada heterogeneidade molecular e clínica. Em Portugal, assim como em outros países europeus, a sua prevalência e espectro mutacional têm vindo a aumentar devido a fluxos migratórios recentes. As abordagens tradicionais de diagnóstico combinam ensaios hematológicos, bioquím...
Background: Technological advances and widely spread screening programs enabled the discovery of ever smaller lesions. As such, in the last years, the tendency has shifted towards lung-sparing procedures. The role of limited surgical excision for small peripheral nodules is currently a topic of heated debate. Aim: In our work, we try to answer whether the segmentectomy could adequately treat the peripheral NSCL...
Introduction: Mesothelioma is a devastating, insidious disease with a long latency period. Its peak incidence occurs in the 5th and 6th decades of life, up to 40 years after asbestos exposure which is strongly related to the disease. The optimal treatment is the object of an intense discussion. Aims: The established outcomes were disease-free survival (DFS) and 1-year survival analyzed in the context of neoadju...
As alterações demográficas, resultam numa população envelhecida e em situação de dependência, aumentando a necessidade de cuidados de longa duração, de institucionalização e de cuidadores informais. O cuidador informal é alguém da rede social da pessoa a quem presta cuidados. O ato de cuidar reveste-se de grande complexidade, podendo conduzir à sobrecarga. A intitucionalização, em Unidades de Cuidados Continuad...
Introduction: Myasthenia gravis (MG) is an autoimmune, neurologic disease that causes a wide range of symptoms. While the transsternal, transcervical and thoracotomy approaches are accepted as effective, there is still debate regarding the VATS approach. Materials and Methods: We analyzed our center’s surgical experience with thymectomy for myasthenia gravis, comparing the results of patients operated on using ...
This study develops a four-item scale to measure the impact of a tourism lifestyle entrepreneur on the touristic experience, and seeks to understand to what extent a tourist perceives, through what is provided, that a tourism business owner, is not a “common entrepreneur”. After an item generation, data was collected from two different surveys with 200 answers, and exploratory and confirmatory factorial analyses...
The need for complete resection of chest wall tumors creates a huge challenge in terms of reconstructing the complex dynamics of the thorax. We are reporting a case of a low-grade fibromyxoid sarcoma (LGFMS) diagnosed in a young male, where the complete resection of the mass, sternum and parcially the pericardium was performed. Subsequently, a composite porous high-density polyethylene StarPore® prosthesis of t...
We report a case of a 67-years old non-smoking female diagnosed with hypertension when 24-years-old and complicated with chronic kidney and hypertensive heart diseases. On CT-Chest an incidental discovery of a lesion (16x14x23mm) adjacent to the abdominal aorta was made. Initially suspected to be paraganglioma, a hypothesis which the subsequent MRI did not exclude. Urine analysis showed normal Metanephrine with...
Based on the literature on social enterprises (SEs), this chapter aims to portray the internationalization of social enterprises by analyzing existing knowledge on the subject. To do so, a literature review addressed the steps and procedures required in the process: the drivers, main models and theories, scaling strategies, market selection decisions, among others. It was possible to conclude that SEs’ internat...