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Influence of fatty acids composition in different tissue of mice feeds with fis...

Quinalha, Flávia Santina Pelissari; Manin, Luciana Pelissari; Antunes, Marina Masetto; Godoy, Guilherme; Galuch, Marília Bellanda; Alves, Eloize Silva

Omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) play an important role in human health. Fish oils enriched with EPA and DHA have commercialized in triacylglycerol (TAG) and ethyl ester forms (EE). In this study, we compared the impact of diets containing fish oil in ethyl ester and triacylglycerol forms as a lipid source in five di...

Date: 2021   |   Origin: Oasisbr

Oral lactate intensifies insulin toxicity during severe insulin-induced hypogly...

Vilela, Vanessa Rodrigues; Antunes, Marina Masetto; Godoi, Vilma Aparecida Ferreira; Travassos, Patricia Batista; Souza, Helenir Medri de

We investigated whether oral lactate could prevent seizures and deaths in mice with severe hypoglycemia induced by a high dose of insulin. For this purpose, mice were fasted for 15 h and then given an intraperitoneal injection of regular insulin (5.0 U/kg or 10.0 U/kg). Immediately after insulin injection, the mice received an oral dose of saline (control), glucose (5.5 mmol/kg), or lactate (18.0 mmol/kg). Gluc...

Date: 2018   |   Origin: Oasisbr

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