36 documents found, page 1 of 4

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The Portuguese observatory on occupational psychosocial factors: contribution f...

Fernandes, C,; Cotrim, T.; Pereira, Anabela; Silva, C.; Bem-Haja, P.; Azevedo, R.; Antunes, S.; Susa Pinto, J.; Silva, I.

To achieve the goal of sustainable employment, considering the profile of the Portuguese working population (PWP), is needed a range of strategies to ensure long, productive, and sustainable careers allied with a better quality of working life, health, and wellbeing, but also with public health policies grounded on scientifically validated and reliable data. This is possible through a comprehensive working syst...


Seabirds as bioindicators of anthropogenic and chemical pollution

Matos, D. M.; Ramos, J. A.; Brandão, L. C.; Bessa, F.; Silva, V.; Rodrigues, I.; Antunes, S.; dos Santos, I.; Coentro, J.; Cunha, S. C.

Background: Marine pollution, caused by anthropogenic debris, is a significant environmental issue that has detrimental effects on marine ecosystems ​[1]​. Finding suitable sentinel species of the human impacts on the oceans, is imperative. As top predators, seabirds are considered sentinels of the marine environment ​[2]​. Objective: To provide quantitative data about the distinctive prevalence of anthropogeni...

Date: 2023   |   Origin: Scientific Letters

Efficacy of the Vaccine Candidate Based on the P0 Peptide against Dermacentor n...

Rodríguez Mallon, A.; Encinosa Guzmán, P.E.; Bello, Y.; Domingos, A.; Antunes, S.; Kopacek, P.; Santos, A.S.; Velez, R.; Perner, J.; Ledesma Bravo, F.L.

The control of ticks through vaccination offers a sustainable alternative to the use of chemicals that cause contamination and the selection of resistant tick strains. However, only a limited number of anti-tick vaccines have reached commercial realization. In this sense, an antigen effective against different tick species is a desirable target for developing such vaccines. A peptide derived from the tick P0 pr...


Rhipicephalus bursa Sialotranscriptomic Response to Blood Feeding and Babesia o...

Antunes, S.; Couto, J.; Ferrolho, J.; Rodrigues, F.; Nobre, J.; Santos, A.S.; Santos-Silva, M.M.; de la Fuente, J.; Domingos, A.

Ticks are among the most prevalent blood-feeding arthropods, and they act as vectors and reservoirs for numerous pathogens. Sialotranscriptomic characterizations of tick responses to blood feeding and pathogen infections can offer new insights into the molecular interplay occurring at the tick-host-pathogen interface. In the present study, we aimed to identify and characterize Rhipicephalus bursa salivary gland...


Molecular heterogeneity of Rhipicephalus sanguineus sensu lato and screening fo...

Santos, G.S.; Couto, J.; Silva-Perdosa, R.; Ferrolho, J.; Santos, A.S.; Santos-Silva, M.M.; Antunes, S.; Domingos, A.

The present study aimed to expand knowledge regarding the molecular characterization of R. sanguineus s.l. in Portugal and to screen for ticks naturally infected with E. canis. A total of 113 R. sanguineus s.l. were collected questing or attached to domestic and wild animals from the 18 administrative regions of mainland Portugal. All the ticks were analyzed for the 16S rRNA and the partial sequences obtained s...


PCR screening of tick-borne agents in sensitive conservation areas, Southeast P...

Santos-Silva, M.M.; Melo, P.; Santos, N.; Antunes, S.; Duarte, L.R.; Ferrolho, J.; Milhano, N.; Santos, P.T.; Domingos, A.; Santos, A.S.

The Southeast region of Portugal, particularly the Guadiana valley, is currently the reintroduction territory of Lynx pardinus (Iberian lynx), one of the most endangered felids in the world that is only found in the Iberian Peninsula. Over the last century, populations have declined, placing L. pardinus at extremely high risk of extinction in the wild and relying on reintroduction projects. Among the aspects ta...


Detection and phylogenetic characterization of Theileria spp. and Anaplasma mar...

Ferrolho, A.; Antunes, S.; Santos, A.S.; Velez, R.; Padre, L.; Cabezas-Cruz, A.; Santos-Silva, M.M.; Domingos, A.

Ticks are obligatory blood-sucking arthropod (Acari:Ixodida) ectoparasites of domestic and wild animals as well as humans. The incidence of tick-borne diseases is rising worldwide, challenging our approach toward diagnosis, treatment and control options. Rhipicephalus bursa Canestrini and Fanzago, 1877, a two-host tick widely distributed in the Palearctic Mediterranean region, is considered a multi-host tick th...


An insight into the transcriptome of Rhipicephalus bursa: differential gene exp...

Couto, J.; Antunes, S.; Ferrolho, J.; Santos, A.S.; Santos-Silva, M.M.; de la Fuente, J.; Domingos, A.

Understanding the paradigm of the pathogen-tick-host triad remains an intricate issue. Basic research focusing on each one of these interplays is necessary to better comprehend this dynamic system. One of such complex association is the Babesia ovis, transmitted by the Rhipicephalus bursa ticks. B. ovis is an intra-erythrocytic protozoan parasite highly pathogenic parasite, causing severe infection in sheep. Pa...


Anaplasma marginale and Theileria annulata in questing ticks from Portugal

Antunes, S.; Ferrolho, J.; Domingues, N.; Santos, A.S.; Santos-Silva, M.M.; Domingos, A.

Ticks are ubiquitous arthropods and vectors of several pathogenic agents in animals and humans. Monitoring questing ticks is of great importance to ascertain the occurrence of pathogens and the potential vector species, offering an insight into the risk of disease transmission in a given area. In this study 428 host-seeking ticks, belonging to nine species of Ixodidae and collected from 17 of the 23 Portuguese ...


Vitellogenin and Lachesin knockdown in Rhipicephalus bursa influence in feeding...

Antunes, S.; Ferrolho, J.; Nobre, J.; Couto, J.; Santos, A.S.; Santos-Silva, M.M.; de la Fuente, J.; Domingos, A.

Rhipicephalus bursa is considered as a multi-host tick being the primary hosts of this species, cattle, sheep and goats. R. bursa is widely distributed in the Mediterranean region and has been described as being involved in the transmission of agents of the genus Anaplasma, Babesia, Theileria, Rickettsia among others, with a known impact on animal health. Control of ticks by vaccination has the advantages of be...


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