19 documents found, page 1 of 2
A Comparative Study of Onychomycosis and Traumatic Toenail Onychodystrophy Derm...
Ramos Pinheiro, R; Dias Domingues, T; Sousa, V; Galhardas, C; Apetato, M; Lencastre, ABackground: Onychomycosis (OM) and traumatic onychodystrophy (OD) are common causes of toenail changes. A clinical diagnosis is often impossible without mycology. Dermoscopy is helpful in this setting but yet underexplored. Prospective comparative studies between OM and OD onychoscopic findings have not been previously performed. Objectives: We sought to determine distinguishing dermoscopic presentations of OM ...
Tinea Faciei in a Central Portuguese Hospital: A 9-Year Survey
Borges, A; Brasileiro, A; Galhardas, C; Apetato, MTinea faciei is a relatively uncommon dermatophytosis that affects the glabrous skin of the face. The aim of this study was to analyse the epidemiologic, clinical and mycological features of tinea faciei cases diagnosed at the Dermatology and Venereology Department of Hospital Santo António dos Capuchos (Lisbon, Portugal). Consecutive cases diagnosed between 2008 and 2016 were studied retrospectively. A total o...
Nodular Vasculitis Associated with Lung Adenocarcinoma
Borges, AS; Brasileiro, A; Apetato, MNodular vasculitis is an uncommon type of panniculitis. It was firstly associated to the infection by Mycobacterium tuberculosis and named erythema induratum of Bazin, however nowadays it has been associated with several other underlying disorders and it is better described as nodular vasculitis. Concerning its relationship with malignant conditions, there is only one reported case, in association with metastat...
The Dark Side of the Light: Mechanisms of Photocarcinogenesis
Valejo Coelho, M; Matos, T; Apetato, MUltraviolet radiation (UVR) can have a beneficial biologic impact on skin, but it is also the most significant environmental risk factor for skin cancer development. Photocarcinogenesis comprises a complex interplay between the carcinogenic UVR, skin, and the immune system. UVB is absorbed by the superficial skin layers and is mainly responsible for direct DNA damage, which, if unrepaired, can lead to mutations...
The Dark Side of the Light: Phototherapy Adverse Effects
Valejo Coelho, M; Apetato, MPhototherapy is a valuable therapeutic tool in Dermatology, but there may be drawbacks. Acute and long-term adverse effects, of variable severity, include skin erythema, xerosis, pruritus, blistering, altered pigmentation, photoaging, and photocarcinogenesis. Despite concerns over the carcinogenic potential of ultraviolet radiation, most studies have not found an increased risk of non-melanoma or melanoma skin ...
Onychomycosis in Patients with Chronic Leg Ulcer and Toenail Abnormalities
Cabete, J; Apetato, M; Galhardas, C; Lestre, SNails have a limited number of reactive patterns to disease. Accordingly, toenail changes of different etiologies may mimic onychomycosis. OBJECTIVE To determine the prevalence of toenail onychomycosis among patients with leg ulcer and toenail abnormalities attending a dermatology clinic. METHODS A cross-sectional study was conducted through the analysis of clinical records and results of mycological examinatio...
Fototerapia como Adjuvante da Terapêutica Biológica na Psoríase
Cabete, J; Serrão, V; Lestre, S; Páris, F; Apetato, MIntrodução: A associação terapêutica é uma estratégia frequentemente usada no tratamento da psoríase. Contudo, a associação de fármacos biológicos com terapêuticas convencionais, e em particular com fototerapia, tem sido pouco explorada. Objectivo: Caracterizar a eficácia e a segurança da associação fototerapia-terapêutica biológica no tratamento da psoríase. Métodos: Foram analisados retrospectivamente os proc...
Phototherapy in Childhood: a 17-Year Retrospective Study Regarding Effectivenes...
Brasileiro, A; Campos, S; Páris, F; Fidalgo, A; Apetato, MIntroduction: Skin diseases in paediatric age are often distressing conditions with significant impact in children’s psychosocial development. Additionally, systemic therapeutic options are often limited in childhood, due to its potential toxicity in this vulnerable group. Phototherapy is therefore an endorsed option for photo-responsive dermatological conditions. Objective and Methods:This observational retros...
Birt-Hogg-Dubé Syndrome
Lencastre, A; Ponte, P; Apetato, M; Nunes, L; Lestre, SA 45-year-old woman with a history of renal carcinoma was observed for facial, cervical and truncal flesh-colored papules. Relatives had similar skin findings and a brother had repeated episodes of pneumothorax. The computerized tomography scan revealed multiple cysts on both lungs. A skin biopsy revealed a perifollicular fibroma. The clinical diagnosis of Birt-Hogg-Dubé syndrome (BHDS) was corroborated by iden...
Case for Diagnosis
Lencastre, A; Cabete, J; Apetato, MAn 83 year-old man was observed for an 8 year-long pruritic, erythematous plaque of the left axilla. He had been continuously medicated with topical antifungals and steroids with occasional symptomatic relief, but with disease progression. After a clinical and histological diagnosis of Extramammary Paget's Disease, a total excision with wide margins was performed. He remains disease-free 12 months after surgery...