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Selection of aptamers against triple negative breast cancer cells using high th...
Ferreira, Débora Carina Gonçalves Abreu; Barbosa, J.; Sousa, Diana Andrade; Silva, C.; Melo, Luís Daniel Rodrigues; Avci-Adali, M.; Wendel, H. P.Triple-negative breast cancer is the most aggressive subtype of invasive breast cancer with a poor prognosis and no approved targeted therapy. Hence, the identification of new and specific ligands is essential to develop novel targeted therapies. In this study, we aimed to identify new aptamers that bind to highly metastatic breast cancer MDA-MB-231 cells using the cell-SELEX technology aided by high throughput...
Date: 2021
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Origin: RepositóriUM - Universidade do Minho