A diastereoselective three-component cascade reaction, catalyzed by p-sulfonic acid calix[4]arene, provides a unique method to access diverse julolidine derivatives in high yields. Additionally, the reaction was also monitored by mass spectrometry and the mechanistic pathway uncovered.
The present work studied the chemical composition of arabica coffee (Coffea arabica L.) and defective beans (black, green and brown beans), from the same origin, submitted to different degrees of roasting. The coffee samples came from the Minas Gerais savannah (“cerrado”). The beverages prepared from defective beans were sourer, probably due to beans fermentation. Also, the presence of defective bea...