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Portuguese recommendations for the use of ultrasound in rheumatology

Polido-Pereira, Joaquim; Serra, Sara; Teixeira, Filipa; Ponte, Cristina; Cerqueira, Marcos; Cruz, Margarida; Araújo, Filipe; Barros, Rita

INTRODUCTION: Ultrasound (US) is a relatively cheap, easily available and reliable method to improve the care of rheumatic patients. However, its use in rheumatology practice is very heterogeneous and needs to be standardized. OBJECTIVES: To develop recommendations for the use of US in rheumatic diseases endorsed by the Portuguese Society of Rheumatology. METHODS: A systematic literature review of the available...


Portuguese recommendations for the use of methotrexate in rheumatic diseases - ...

Duarte, Ana Catarina; Santos-Faria, Daniela; Gonçalves, Maria João; Sepriano, Alexandre; Mourão, Ana Filipa; Duarte, Cátia; Neves, Joana Sousa

BACKGROUND: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying anti-rheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. OBJECTIVES: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic dise...


Prevalence of rheumatic and musculoskeletal diseases and their impact on health...

Branco, Jaime C.; Rodrigues, Ana M.; Gouveia, Nélia; Eusébio, Mónica; Ramiro, Sofia; Machado, Pedro M.; Da Costa, Leonor Pereira; Mourão, Ana Filipa

Objectives: To estimate the national prevalence of rheumatic and musculoskeletal diseases (RMDs) in the adult Portuguese population and to determine their impact on health-related quality of life (HRQoL), physical function, anxiety and depression. Methods: EpiReumaPt is a national health survey with a three-stage approach. First, 10 661 adult participants were randomly selected. Trained interviewers undertook s...


Outcomes assessed in trials of gout and accordance with OMERACT-proposed domains

Araújo, Filipe; Cordeiro, Inês; Ramiro, Sofia; Falzon, Louise; Branco, Jaime; Buchbinder, Rachelle

Publisher Copyright: © The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.; Objective. The aim of this study was to systematically review outcome domains and measurement tools used in gout trials and their accordance with the preliminary OMERACT gout recommendations published in 2005.Methods. Randomized controlled trials (RCTs) and quasi-...


Cervical spine involvement as initial manifestation of rheumatoid arthritis: a ...

Araújo, Filipe; Silva, Inês; Sepriano, Alexandre; Reizinho, Carla; Marques, Luís; Nero, Patrícia; Branco, Jaime

Rheumatoid arthritis' synovitis affects mostly small hand and feet joints, although it may compromise any joint with a synovial lining. Cervical involvement occurs usually in longstanding disease in over half of these patients. We report the case of a 35-year old male patient who was referred to our outpatient clinic for a 2-year severe and disabling inflammatory neck pain, with incomplete response to intramusc...


EpiReumaPt- the study of rheumatic and musculoskeletal diseases in Portugal

Maria Rodrigues, Ana; Gouveia, Nélia; Da Costa, Leonor Pereira; Eusébio, Mónica; Ramiro, Sofia; Machado, Pedro; Mourão, Ana Filipa; Silva, Inês

Rheumatic and musculoskeletal diseases (RMD) are prevalent and leading causes of disability and consumption of healthcare and social resources. EpiReumaPt is a national population-based survey developed by the Portuguese Society of Rheumatology that aimed to estimate the prevalence of RMDs and determine their impact on function, quality of life, mental health and use of healthcare resources. This article descri...


Off-label use of rituximab in systemic rheumatic diseases

Araújo, Filipe; Silva, Inês; Sepriano, Alexandre; Nero, Patrícia; Branco, Jaime

B-cells play an important role not only in cellular but also in humoral immunity through differentiation into plasma cells and antibody production. B-cell depletion may, theoretically, change the course of systemic rheumatic diseases (SRD) in which self-reactive antibodies are part of the pathogenic pathway. In Rheumatology, anti-B-cell antibody Rituximab is currently licensed for the treatment of rheumatoid ar...


Reconfiguração Dinâmica Estruturada de Workflows de Serviços Web

Araújo, Filipe; Gomes, Maria Cecília Farias Lorga; Paulino, Hervé Miguel Cordeiro

O conceito de serviço consiste numa abstracção simples mas poderosa para representar/integrar entidades de diferentes contextos, e.g. serviços Web da área de nego ́cio, serviços computacionais em Grid, ou Internet of Things. Os sistemas de gestão de workflows, por seu lado, são uma solução standard para a especificação/execução da composição de serviços, para os quais ́e necessário garantir mecanismos adicionai...


Accessing wireless sensor networks via dynamically reconfigurable interaction m...

Gomes, Maria Cecília Farias Lorga; Paulino, Hervé Miguel Cordeiro; Baptista, Adérito; Araújo, Filipe

The Wireless Sensor Networks (WSNs) technology is already perceived as fundamental for science across many domains, since it provides a low cost solution for environment monitoring. WSNs representation via the service concept and its inclusion in Web environments, e.g. through Web services, supports particularly their open/standard access and integration. Although such Web enabled WSNs simplify data access, net...


Klebsiella pneumoniae spinal epidural abscess treated conservatively

Araújo, Filipe; Ribeiro, Célia; Silva, Inês; Nero, Patrícia; Branco, Jaime

Spinal infections are rare but potentially life-threate -ning disorders. A high level of clinical suspicion is neces sary for rapid diagnosis and treatment initiation. The treatment combines both antibiotics and surgical intervention in the vast majority of cases. The authors report the case of a 84-year old female patient with a three week history of persistent lumbar back pain radiating to both thighs followi...


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