Background/Objectives: Acute kidney injury (AKI) is a potential complication of cardiovascular disorders and is associated with worse outcome. The aim of this study was to assess the incidence of early AKI after endovascular therapy for acute ischemic stroke, identify predictors for this complication, and test the association between AKI and mortality or death or dependency. Methods: This was a single-center co...
<jats:p>A Ama, profissional responsável por assegurar cuidados básicos a crianças, passou a estar enquadrada legalmente, em Portugal, a partir do Decreto-lei n.º158/84. Este elencava requisitos e exigências para todos aqueles cujo objetivo fosse tornar a sua habitação o local de permanência de quatro crianças, entre os três meses e os três anos. Em 2022, ao abrigo da legislação que regulamenta as condições para...
A Ama, profissional responsável por assegurar cuidados básicos a crianças, passou a estar enquadrada legalmente, em Portugal, a partir do Decreto-lei n.º158/84. Este elencava requisitos e exigências para todos aqueles cujo objetivo fosse tornar a sua habitação o local de permanência de quatro crianças, entre os três meses e os três anos. Em 2022, ao abrigo da legislação que regulamenta as condições para a concr...
OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...
Purpose: Approximately 25% of older inpatients have an indwelling urinary catheter (IUC), 45-54% unnecessarily. This study aims to describe the prevalence, indications, and complications of IUC use in Portuguese older inpatients. Methods: Multicentric, cross-sectional, observational study conducted in Portuguese internal medicine wards (UriCath). Results: Of a total of 3135 inpatients from 39 hospitals, we incl...
OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...
The occurrence of protein synthesis errors (mistranslation) above the typical mean mistranslation level of 10−4 is mostly deleterious to yeast, zebrafish and mammal cells. Previous yeast studies have shown that mistranslation affects fitness and deregulates genes related to lipid metabolism, but there is no experimental proof that such errors alter yeast lipid profiles. We engineered yeast strains to misincorpo...